D-Pro-Phe-Arg-Chloromethylketone
Based on 1 publication(s) in Google Scholar
D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation.
For research use only. We do not sell to patients.
- Purity: 99.24%
- CAS No.: 88546-74-1
- Formula: C21H31ClN6O3
- Molecular Weight:450.96
-
Storage:
Sealed storage, away from moisture and light.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) D-Pro-Phe-Arg-Chloromethylketone
More
Biological Activity
Description
Chemical Information
-
CAS No. 88546-74-1
-
Appearance Solid
-
Molecular Weight 450.96
-
Formula C21H31ClN6O3
-
Color White to off-white
-
Sequence
{d-Pro}-Phe-{Arg-Chloromethylketone}
-
Sequence Shortening
{d-Pro}-F-{Arg-Chloromethylketone}
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture and light
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Immunity
2026 Jun 9;59(6):1651-1666.e8. PMID: 42140192
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (221.75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2175 mL | 11.0875 mL | 22.1749 mL | 55.4373 mL |
| 5 mM | 0.4435 mL | 2.2175 mL | 4.4350 mL | 11.0875 mL | |
| 10 mM | 0.2217 mL | 1.1087 mL | 2.2175 mL | 5.5437 mL | |
| 15 mM | 0.1478 mL | 0.7392 mL | 1.4783 mL | 3.6958 mL | |
| 20 mM | 0.1109 mL | 0.5544 mL | 1.1087 mL | 2.7719 mL | |
| 25 mM | 0.0887 mL | 0.4435 mL | 0.8870 mL | 2.2175 mL | |
| 30 mM | 0.0739 mL | 0.3696 mL | 0.7392 mL | 1.8479 mL | |
| 40 mM | 0.0554 mL | 0.2772 mL | 0.5544 mL | 1.3859 mL | |
| 50 mM | 0.0443 mL | 0.2217 mL | 0.4435 mL | 1.1087 mL | |
| 60 mM | 0.0370 mL | 0.1848 mL | 0.3696 mL | 0.9240 mL | |
| 80 mM | 0.0277 mL | 0.1386 mL | 0.2772 mL | 0.6930 mL | |
| 100 mM | 0.0222 mL | 0.1109 mL | 0.2217 mL | 0.5544 mL |
D-Pro-Phe-Arg-Chloromethylketone Related Classifications
HY-P4245 Related Classifications
Powered by Bioz