1. D-α-Aminocyclohexylacetic acid

D-α-Aminocyclohexylacetic acid  (Synonyms: (R)-2-Cyclohexyl-2-aminoethanoic acid; D-Cyclohexylglycine; D-α-Aminocyclohexaneacetic acid)

Cat. No.: HY-42354
Handling Instructions

D-α-Aminocyclohexylacetic acid is a Glycine (HY-Y0966) derivative.

For research use only. We do not sell to patients.

D-α-Aminocyclohexylacetic acid Chemical Structure

D-α-Aminocyclohexylacetic acid Chemical Structure

CAS No. : 14328-52-0

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Description

D-α-Aminocyclohexylacetic acid is a Glycine (HY-Y0966) derivative[1].

In Vitro

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

157.21

Formula

C8H15NO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](C1CCCCC1)N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 8.33 mg/mL (52.99 mM; ultrasonic and adjust pH to 3 with HCl)

H2O : 3.33 mg/mL (21.18 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.3609 mL 31.8046 mL 63.6092 mL
5 mM 1.2722 mL 6.3609 mL 12.7218 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 1 mg/mL (6.36 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 6.3609 mL 31.8046 mL 63.6092 mL 159.0230 mL
5 mM 1.2722 mL 6.3609 mL 12.7218 mL 31.8046 mL
10 mM 0.6361 mL 3.1805 mL 6.3609 mL 15.9023 mL
15 mM 0.4241 mL 2.1203 mL 4.2406 mL 10.6015 mL
20 mM 0.3180 mL 1.5902 mL 3.1805 mL 7.9511 mL
H2O 25 mM 0.2544 mL 1.2722 mL 2.5444 mL 6.3609 mL
30 mM 0.2120 mL 1.0602 mL 2.1203 mL 5.3008 mL
40 mM 0.1590 mL 0.7951 mL 1.5902 mL 3.9756 mL
50 mM 0.1272 mL 0.6361 mL 1.2722 mL 3.1805 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
D-α-Aminocyclohexylacetic acid
Cat. No.:
HY-42354
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