1. Metabolic Enzyme/Protease
    Immunology/Inflammation
  2. Endogenous Metabolite
    Arginase

DL-Norvaline (Synonyms: 2-Aminopentanoic acid)

Cat. No.: HY-W010510 Purity: >97.0%
Handling Instructions

DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.

For research use only. We do not sell to patients.

DL-Norvaline Chemical Structure

DL-Norvaline Chemical Structure

CAS No. : 760-78-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
5 g USD 50 In-stock
Estimated Time of Arrival: December 31
10 g   Get quote  
50 g   Get quote  

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  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

DL-Norvaline, a derivative of L-norvaline, L-norvaline is a non-competitive inhibitor of arginase.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

DL-Norvaline, a derivative of L-norvaline[1], L-norvaline is a non-competitive inhibitor of arginase[2].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.5361 mL 42.6803 mL 85.3606 mL
5 mM 1.7072 mL 8.5361 mL 17.0721 mL
10 mM 0.8536 mL 4.2680 mL 8.5361 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Cell Assay

A murine macrophage cell line (RAW264.7) is used throughout the study, RAW264.7 cells are induced by A. actinomycetemcomitans-lipopolysaccharide, cells are incubated with various concentrations of L-norvaline or DL-norvaline (0.01, 0.1, 1, 10 mM) and 10 μg of A. actinomycetemcomitans-lipopolysaccharide. In other experiments, cells are incubated with antimurine CD14 or antimurine toll-like receptor 2 and 4 antibody at room temperature for 1 h, washed three times, and then stimulated with 10 μg of A. actinomycetemcomitans-lipopolysaccharide. All experiments are repeated three times, each consisting of triplicate cultures[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

117.15

Formula

C₅H₁₁NO₂

CAS No.

760-78-1

SMILES

CCCC(N)C(O)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Purity: >97.0%

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
DL-Norvaline
Cat. No.:
HY-W010510
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DL-Norvaline

Cat. No.: HY-W010510