RIPK1-IN-43
RIPK1-IN-43 is a triazolopyridine compound and also a RIPK1 inhibitor. RIPK1-IN-43 can be used in the research of diseases associated with abnormal RIPK1, such as multiple sclerosis, Parkinson's disease, non-alcoholic steatohepatitis, etc.
For research use only. We do not sell to patients.
- Formula: C22H17F4N9
- Molecular Weight:483.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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RIPK1 |
RIPK1-IN-43 (Example 2) exhibits an IC50 of 4.2 nM in the high-content assay of MLKL phosphorylation in HT29‑L23 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 483.42
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Formula C22H17F4N9
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SMILES
CC(F)(F)C(C1=CC(F)=CC(F)=C1)N(N=C2)N=C2C3=NC(C4=C(C)C5=NC(N)=NN5C=C4)=CN=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)