1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. nAChR
  3. Dihydro-β-erythroidine

Dihydro-β-erythroidine 

Cat. No.: HY-N10497
Handling Instructions

Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced.

For research use only. We do not sell to patients.

Dihydro-β-erythroidine Chemical Structure

Dihydro-β-erythroidine Chemical Structure

CAS No. : 23255-54-1

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Description

Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[1][2].

In Vivo

Dihydro-β-erythroidine (0.5, 1.6, 5.0 mg/kg; s.c.) blocks the discriminative stimulus properties of nicotine in rats[1].
Dihydro-β-erythroidine (100 ng) shows antagonism of the anxiolytic effect of nicotine in the dorsal raphe´ nucleus in rats[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 200-250 g male hooded Lister rats[1]
Dosage: 0.5, 1.6, 5.0 mg/kg
Administration: S.c.
Result: Prevented the development of CTAs (conditioned taste aversion) and blocked the discriminative stimulus effect of nicotine (0.2 or 0.4 mg/kg SC) for 45 min after its administration.
Molecular Weight

275.34

Formula

C16H21NO3

CAS No.
SMILES

CO[[email protected]]1CC=C2CCN3CCC4=C([[email protected]@]32C1)CC(OC4)=O

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Dihydro-β-erythroidine
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