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Cat. No.: HY-Z15599

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Adlupulone

Name: Adlupulone
Brand: MedChemExpress
SKU: HY-Z15599
Availability: PreOrder

(Synonyms: Phloroglucinol impurity X)

Adlupulone (Phloroglucinol impurity X) is an antibacterial agent with an MIC of 0.98 μg/mL and an MBC of 3.91 μg/mL against Bacillus subtilis. Adlupulone is found in auxin-induced root cultures of Hypericum perforatum and in female flowers of hops (Humulus lupulus L.). Adlupulone can be used in research related to Bacillus subtilis infection.

For research use only. We do not sell to patients.

CAS No.: 31769-60-5
Formula: C₂₆H₃₈O₄
Molecular Weight:414.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Adlupulone Chemical Structure

CAS No.: 31769-60-5

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Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

Adlupulone (16-24 h) potently inhibits and kills Bacillus subtilis ATCC6051 in vitro with an MIC of 0.98 μg/mL and MBC of 3.91 μg/mL, and contributes moderately to the antibacterial activity of HHT hop extract with an AAV of 0.80^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 31769-60-5
Molecular Weight 414.59
Formula C₂₆H₃₈O₄
SMILES

O=C(C=1C(O)=C(C(=O)C(C1O)(CC=C(C)C)CC=C(C)C)CC=C(C)C)C(C)CC
Synonyms

Phloroglucinol impurity X
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gaid M, et al. Hyperforin production in Hypericum perforatum root cultures. Journal of biotechnology. 2016 Mar 20;222:47-55.

[2]. Li Y, et al. Identification of colupulone and lupulone as the main contributors to the antibacterial activity of hop extracts using activity-guided fractionation and metabolome analysis. Food research international (Ottawa, Ont.). 2023 Jul;169:112832. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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