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Cat. No.: HY-N12716

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Longipedunin A

Longipedunin A is a HIV-1 Protease inhibitor with an IC₅₀ value of 50 µg/mL.

For research use only. We do not sell to patients.

CAS No.: 886441-72-1
Formula: C₃₁H₃₂O₈
Molecular Weight:532.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Longipedunin A Chemical Structure

CAS No.: 886441-72-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Longipedunin A is a HIV-1 Protease inhibitor with an IC₅₀ value of 50 µg/mL^[1].

IC₅₀ & Target

IC₅₀: 50 µg/mL (HIV-1 Protease)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	ED₅₀	>=5 μg/mL Compound: 4	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 16792420]
KB	ED₅₀	>=5 μg/mL Compound: 4	Cytotoxicity against human KB cells by MTT assay Cytotoxicity against human KB cells by MTT assay	[PMID: 16792420]

Chemical Information

CAS No. 886441-72-1
Molecular Weight 532.58
Formula C₃₁H₃₂O₈
SMILES

OC(C(OC)=C(OC)C=C1C[C@@H](C)[C@@H](C)[C@H]2OC(/C=C/C3=CC=CC=C3)=O)=C1C4=C2C=C(OCO5)C5=C4OC
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sun QZ, et al. Three new lignans, longipedunins A-C, from Kadsura longipedunculata and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo). 2006 Jan;54(1):129-32. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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