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Cat. No.: HY-187412A

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DOPE-PEG2000-VHPKQHRGGSKGC

DOPE-PEG2000-VHPKQHRGGSKGC is an amphiphilic lipid-PEG-peptide conjugate consisting of DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the VHPKQHRGGSKGC peptide, a tumor-targeting peptide containing a terminal cysteine for conjugation. DOPE-PEG2000-VHPKQHRGGSKGC is used for tumor-targeted drug delivery via liposome and nanoparticle surface modification.

For research use only. We do not sell to patients.

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DOPE-PEG2000-VHPKQHRGGSKGC Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- In Vitro
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Biological Activity

Description

In Vitro

DOPE-PEG2000-VHPKQHRGGSKGC: surface functionalization of liposomes and nanoparticles for tumor-targeted drug delivery, enabling selective drug accumulation in tumor tissues.
Structural composition:
(1) DOPE; a fusogenic phospholipid with two oleoyl chains that anchors into lipid bilayers and promotes pH-responsive membrane fusion for intracellular cargo release;
(2) PEG2000; a hydrophilic polymer chain that provides steric stabilization, reduces protein adsorption and immune clearance, and extends circulation half-life;
(3) VHPKQHRGGSKGC peptide; a tumor-targeting peptide that specifically recognizes and binds to markers on tumor cells, with the C-terminal cysteine providing a thiol group for stable conjugation to maleimide-functionalized PEG, directing nanocarriers to tumor tissues for enhanced therapeutic efficacy.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

SMILES

[DOPE-PEG2000-VHPKQHRGGSKGC]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.