2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. DosatiLink-1

DosatiLink-1 is an Abelson murine leukemia (ABL) enzyme inhibitor.

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DosatiLink-1

DosatiLink-1 Estructura química

No. CAS : 2941512-37-2

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DosatiLink-1 Related Antibodies

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Abl Bcr-Abl

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Descripciòn

DosatiLink-1 is an Abelson murine leukemia (ABL) enzyme inhibitor[1].

Cellular Effect
Cell Line Type Value Description References
K562 EC50
2.47 nM
Compound: Dosati Link-1
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
[PMID: 37849551]
K562 EC50
> 300 nM
Compound: Dosati Link-1
Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
[PMID: 37849551]
Peso molecular

1517.52

Fòrmula

C69H93Cl2F2N13O17S
No. CAS
SMILES

O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(C1CCN(C2=C(C3=CC=NN3)C=C(C(NC4=CC=C(OC(F)(Cl)F)C=C4)=O)C=N2)CC1)=O)N5CCN(C6=CC(NC7=NC=C(C(NC8=C(Cl)C=CC=C8C)=O)S7)=NC(C)=N6)CC5
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
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DosatiLink-1 Related Classifications

  • Calculadora de molaridad

  • Calculadora de dilución

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DosatiLink-12941512-37-2DosatiLink1DosatiLink 1Bcr-AblAbelson murine leukemiaInhibitorinhibitorinhibit

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Nombre del producto:
DosatiLink-1
Cat. No.:
HY-155288
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