country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-172738

Copy Link Print Information

E3 Ligase Ligand-linker Conjugate 175

E3 Ligase Ligand-linker Conjugate 175 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 175 can be used to synthesize PROTAC SMARCA2 degrader-33 (HY-172735).

For research use only. We do not sell to patients.

Formula: C₃₂H₄₃N₅O₆S
Molecular Weight:625.78

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

E3 Ligase Ligand-linker Conjugate 175 Chemical Structure

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

E3 Ligase Ligand-linker Conjugate 175 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 175 can be used to synthesize PROTAC SMARCA2 degrader-33 (HY-172735)^[1]^[2].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 625.78
Formula C₃₂H₄₃N₅O₆S
SMILES

CC1=C(SC=N1)C2=CC=C(C=C2)[C@@H](NC([C@@H]3C[C@H](CN3C([C@H](C(C)C)C4=CC(O[C@H](CN5CC[C@H](C5)O)C)=NO4)=O)O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Michael Hulse, et al. Abstract 3263: Preclinical characterization of PRT3789, a potent and selective SMARCA2 targeted degrader. June 2022Cancer Research 82(12_Supplement):3263-3263.

[2]. Discovery of PRT3789, a first-in-human, highly potent and selective SMARCA2 targeted protein degrader.

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

E3 Ligase Ligand-linker Conjugate 175

100 mg Get Quote

Subscribe to the

MedChemExpress

Newsletter

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

E3 Ligase Ligand-linker Conjugate 175

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 175 Related Classifications

HY-172738 Related Classifications

Bioz

Keywords

Your Recently Viewed Products