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Cat. No.: HY-173424

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E3 Ligase Ligand-linker Conjugate 178

E3 Ligase Ligand-linker Conjugate 178 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 178 can be used to synthesize MS2133 (HY-173422).

For research use only. We do not sell to patients.

CAS No.: 2768514-43-6
Formula: C₃₄H₄₉FN₆O₅S
Molecular Weight:672.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

E3 Ligase Ligand-linker Conjugate 178 Chemical Structure

CAS No.: 2768514-43-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

E3 Ligase Ligand-linker Conjugate 178 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 178 can be used to synthesize MS2133 (HY-173422)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2768514-43-6
Molecular Weight 672.85
Formula C₃₄H₄₉FN₆O₅S
SMILES

O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C3=CC=C(C4=C(C)N=CS4)C=C3)CC(NCCCCCCN)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yim H, et al. Discovery of the first-in-class DOT1L PROTAC degrader. Eur J Med Chem. 2025 Jul 5;291:117595. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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E3 Ligase Ligand-linker Conjugate 178

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E3 Ligase Ligand-linker Conjugate 178

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E3 Ligase Ligand-linker Conjugate 178 Related Classifications

HY-173424 Related Classifications

Bioz

Keywords

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