Epsilon-(gamma-glutamyl)-lysine TFA (Standard)
Based on 1 Customer Validation
Epsilon-(gamma-glutamyl)-lysine TFA (Standard) (H-Glu(H-Lys-OH)-OH TFA (Standard)) is the analytical standard of Epsilon-(gamma-glutamyl)-lysine TFA (HY-113089A). This product is intended for research and analytical applications. Epsilon-(gamma-glutamyl)-lysine TFA (H-Glu (H-Lys-OH)-OH) is an isodipeptide formed during the proteolytic degradation of proteins containing Nε-(γ-glutamyl)-lysine cross-links. Epsilon-(gamma-glutamyl)-lysine TFA serves as a substrate for γ-glutamylamine cyclotransferase, which specifically cleaves it. Epsilon-(gamma-glutamyl)-lysine TFA is applicable to studies related to transglutaminase-mediated protein cross-linking and turnover, γ-glutamylamine cyclotransferase activity, glaucoma, and tissue scar formation.
For research use only. We do not sell to patients.
- Purity : 99.07%
- Formula: C15H23F6N3O9
- Molecular Weight:503.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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Appearance Solid
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Molecular Weight 503.35
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Formula C15H23F6N3O9
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Color White to off-white
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SMILES
OC([C@@H](N)CCC(NCCCC[C@H](N)C(O)=O)=O)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
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Synonyms
H-Glu(H-Lys-OH)-OH TFA (Standard); γ-Glu-ε-Lys TFA (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[2]. El Nahas AM, et al. Elevated ε-(γ-Glutamyl)lysine in Human Diabetic Nephropathy Results from Increased Expression and Cellular Release of Tissue Transglutaminase. Nephron Clin Pract. 2004;97:c108-c117. [Content Brief]
[3]. Priglinger SG, et al. Potential role of tissue transglutaminase in glaucoma filtering surgery. Investigative ophthalmology & visual science. 2006 Sep;47(9):3835-45. [Content Brief]
Keywords
- Epsilon-(gamma-glutamyl)-lysine TFA (Standard)
- H-Glu(H-Lys-OH)-OH TFA (Standard)
- γ-Glu-ε-Lys TFA (Standard)
- Reference Standards
- Endogenous Metabolite
- fibronectin
- trabeculectomy models
- Chinese-hamster ovary cells
- extracellular matrix
- glaucoma
- diabetic nephropathy
- γ-glutamylamine cyclotransferase
- TGF-β2
- renal scarring
- transglutaminase
- Inhibitor
- inhibitor
- inhibit