FAK ligand-2-C6-amine
FAK ligand-2-C6-amine is a target protein ligand linker conjugate that contains a FAK ligand (HY-151010) and a PROTAC linker (HY-W011561), which can recruit E3 ligases. FAK ligand-2-C6-amine can be used for synthesis of BSJ-04-146 (HY-179512).
For research use only. We do not sell to patients.
- CAS No.: 2414478-60-5
- Formula: C35H47F3N6O2
- Molecular Weight:640.78
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
FAK PROTACs contain two different ligands connected by a linker; one is an E3 ligase ligand (Thalidomide-O-COOH) (HY-103597) and the other is for Ligands of FAK target protein (FAK ligand-2) (HY-151010). PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2414478-60-5
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Molecular Weight 640.78
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Formula C35H47F3N6O2
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SMILES
O=C(NC)C1=CC=CC=C1NC2=CC(NC3=CC(C)=C(C4CCN(CCCCCCN)CC4)C=C3OC(C)C)=NC=C2C(F)(F)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)