Boc-NH-C6-Br
Based on 1 Customer Validation
Boc-NH-C6-Br is a non-cleavable linker used for antibody-drug conjugates (ADC).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 98.0%
- CAS No.: 142356-33-0
- Formule: C11H22BrNO2
- Masse moléculaire:280.20
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Stockage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
[1]|
Non-cleavable Linker |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 142356-33-0
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Appearance Solid-Liquid Mixture
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Masse moléculaire 280.20
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Formule C11H22BrNO2
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Color Colorless to off-white
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SMILES
O=C(OC(C)(C)C)NCCCCCCBr
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 40 mg/mL (142.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (266 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5689 mL | 17.8444 mL | 35.6888 mL | 89.2220 mL |
| 5 mM | 0.7138 mL | 3.5689 mL | 7.1378 mL | 17.8444 mL | |
| 10 mM | 0.3569 mL | 1.7844 mL | 3.5689 mL | 8.9222 mL | |
| 15 mM | 0.2379 mL | 1.1896 mL | 2.3793 mL | 5.9481 mL | |
| 20 mM | 0.1784 mL | 0.8922 mL | 1.7844 mL | 4.4611 mL | |
| 25 mM | 0.1428 mL | 0.7138 mL | 1.4276 mL | 3.5689 mL | |
| 30 mM | 0.1190 mL | 0.5948 mL | 1.1896 mL | 2.9741 mL | |
| 40 mM | 0.0892 mL | 0.4461 mL | 0.8922 mL | 2.2305 mL | |
| 50 mM | 0.0714 mL | 0.3569 mL | 0.7138 mL | 1.7844 mL | |
| 60 mM | 0.0595 mL | 0.2974 mL | 0.5948 mL | 1.4870 mL | |
| 80 mM | 0.0446 mL | 0.2231 mL | 0.4461 mL | 1.1153 mL | |
| 100 mM | 0.0357 mL | 0.1784 mL | 0.3569 mL | 0.8922 mL |
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