Boc-NH-C6-Br
Based on 1 Customer Validation
Boc-NH-C6-Br is a non-cleavable linker used for antibody-drug conjugates (ADC).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 98.0%
- CAS 番号: 142356-33-0
- 分子式: C11H22BrNO2
- 分子量:280.20
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
IC50 & Target
[1]|
Non-cleavable Linker |
体外実験
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 142356-33-0
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性状 Solid-Liquid Mixture
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分子量 280.20
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分子式 C11H22BrNO2
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Color Colorless to off-white
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SMILES
O=C(OC(C)(C)C)NCCCCCCBr
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別名
6-(Boc-amino)hexyl bromide
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 40 mg/mL (142.76 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (476 KB)
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- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5689 mL | 17.8444 mL | 35.6888 mL | 89.2220 mL |
| 5 mM | 0.7138 mL | 3.5689 mL | 7.1378 mL | 17.8444 mL | |
| 10 mM | 0.3569 mL | 1.7844 mL | 3.5689 mL | 8.9222 mL | |
| 15 mM | 0.2379 mL | 1.1896 mL | 2.3793 mL | 5.9481 mL | |
| 20 mM | 0.1784 mL | 0.8922 mL | 1.7844 mL | 4.4611 mL | |
| 25 mM | 0.1428 mL | 0.7138 mL | 1.4276 mL | 3.5689 mL | |
| 30 mM | 0.1190 mL | 0.5948 mL | 1.1896 mL | 2.9741 mL | |
| 40 mM | 0.0892 mL | 0.4461 mL | 0.8922 mL | 2.2305 mL | |
| 50 mM | 0.0714 mL | 0.3569 mL | 0.7138 mL | 1.7844 mL | |
| 60 mM | 0.0595 mL | 0.2974 mL | 0.5948 mL | 1.4870 mL | |
| 80 mM | 0.0446 mL | 0.2231 mL | 0.4461 mL | 1.1153 mL | |
| 100 mM | 0.0357 mL | 0.1784 mL | 0.3569 mL | 0.8922 mL |