Fmoc-NH-PEG5-C2-NH2 hydrochloride
Based on 1 Customer Validation
Fmoc-NH-PEG5-C2-NH2 hydrochloride is a PEG-based PROTAC linker. Fmoc-NH-PEG5-C2-NH2 hydrochloride can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.98%
- Formula: C27H39ClN2O7
- Molecular Weight:539.06
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Oil
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Molecular Weight 539.06
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Formula C27H39ClN2O7
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Color Off-white to light yellow
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SMILES
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCN.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (185.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8551 mL | 9.2754 mL | 18.5508 mL | 46.3770 mL |
| 5 mM | 0.3710 mL | 1.8551 mL | 3.7102 mL | 9.2754 mL | |
| 10 mM | 0.1855 mL | 0.9275 mL | 1.8551 mL | 4.6377 mL | |
| 15 mM | 0.1237 mL | 0.6184 mL | 1.2367 mL | 3.0918 mL | |
| 20 mM | 0.0928 mL | 0.4638 mL | 0.9275 mL | 2.3189 mL | |
| 25 mM | 0.0742 mL | 0.3710 mL | 0.7420 mL | 1.8551 mL | |
| 30 mM | 0.0618 mL | 0.3092 mL | 0.6184 mL | 1.5459 mL | |
| 40 mM | 0.0464 mL | 0.2319 mL | 0.4638 mL | 1.1594 mL | |
| 50 mM | 0.0371 mL | 0.1855 mL | 0.3710 mL | 0.9275 mL | |
| 60 mM | 0.0309 mL | 0.1546 mL | 0.3092 mL | 0.7730 mL | |
| 80 mM | 0.0232 mL | 0.1159 mL | 0.2319 mL | 0.5797 mL | |
| 100 mM | 0.0186 mL | 0.0928 mL | 0.1855 mL | 0.4638 mL |
Fmoc-NH-PEG5-C2-NH2 hydrochloride Related Classifications
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