FXR/TGR5 agonist 1
Based on 1 Customer Validation
FXR/TGR5 agonist 1 has agonist action on FXR and TGR5, and can be used for the research of fatty liver disease.
For research use only. We do not sell to patients.
- Purity: 98.03%
- CAS No.: 2677689-72-2
- Formula: C31H32ClN3O3
- Molecular Weight:530.06
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 2677689-72-2
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Appearance Solid
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Molecular Weight 530.06
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Formula C31H32ClN3O3
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Color White to off-white
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SMILES
O=C(C1=C(C)C=NC=C1)N(C2=CC(OC)=CC(Cl)=C2)CC3(CC4)CCC4(C5=CC=C(OC)C(C#N)=C5)CC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 20 mg/mL (37.73 mM; ultrasonic and adjust pH to 3 with 1 M HCl; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8866 mL | 9.4329 mL | 18.8658 mL | 47.1645 mL |
| 5 mM | 0.3773 mL | 1.8866 mL | 3.7732 mL | 9.4329 mL | |
| 10 mM | 0.1887 mL | 0.9433 mL | 1.8866 mL | 4.7164 mL | |
| 15 mM | 0.1258 mL | 0.6289 mL | 1.2577 mL | 3.1443 mL | |
| 20 mM | 0.0943 mL | 0.4716 mL | 0.9433 mL | 2.3582 mL | |
| 25 mM | 0.0755 mL | 0.3773 mL | 0.7546 mL | 1.8866 mL | |
| 30 mM | 0.0629 mL | 0.3144 mL | 0.6289 mL | 1.5721 mL |