2. Gene
  3. Mir145 - microRNA 145 Gene

Mir145 - microRNA 145 Gene

  • Gene
  • Agent
  • Ortholog
Rattus norvegicus

Also known as rno-mir-145

Gene ID: 100314036 | Gene type: ncRNA

About Mir145

Summary

MicroRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted MicroRNA stem-loop. [provided by RefSeq, Sep 2009]

Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to hydroperoxide IEP
IEP: Inferred from expression pattern
23028672 RGD
involved in positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching IMP
IMP: Inferred from mutant phenotype
19542014 RGD
involved in response to alkaloid IEP
IEP: Inferred from expression pattern
35369850 RGD
involved in response to ischemia IEP
IEP: Inferred from expression pattern
23166305 RGD
involved in retina layer formation IMP
IMP: Inferred from mutant phenotype
34291866 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Related Agents

Approval
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0185 Lidocaine 99.96% Yes
HY-B0185A Lidocaine hydrochloride 99.84% Yes
HY-B0185B Lidocaine hydrochloride hydrate 99.80% Yes
Pre-clinical Phase
Bioactive Molecules (27)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0185R Lidocaine (Standard) 99.97% Unkown
HY-B0185S1 Lidocaine-d10 99.58% Unkown
HY-R00282 hsa-miR-145-5p mimic 98.34% Unkown
HY-RI00282 hsa-miR-145-5p inhibitor 98.19% Unkown
HY-B0185AS Lidocaine-d10 hydrochloride 99.79% Unkown
HY-R00282A hsa-miR-145-5p agomir 99.68% Unkown
HY-RI00282A hsa-miR-145-5p antagomir 95.09% Unkown
HY-B0185G Lidocaine (GMP) / Unkown
HY-R00281 hsa-miR-145-3p mimic 98.54% Unkown
HY-R02680 mmu-miR-145b mimic 97.02% Unkown
HY-RI02680 mmu-miR-145b inhibitor 95.41% Unkown
HY-B0185AS1 Lidocaine-d6 hydrochloride / Unkown
HY-R00281A hsa-miR-145-3p agomir / Unkown
HY-R02679 mmu-miR-145a-3p mimic / Unkown
HY-R02679A mmu-miR-145a-3p agomir / Unkown
HY-R02680A mmu-miR-145b agomir / Unkown
HY-R04235 rno-miR-145-3p mimic / Unkown
HY-R04235A rno-miR-145-3p agomir / Unkown
HY-RI00281 hsa-miR-145-3p inhibitor / Unkown
HY-RI00281A hsa-miR-145-3p antagomir / Unkown
HY-RI02679 mmu-miR-145a-3p inhibitor / Unkown
HY-RI02679A mmu-miR-145a-3p antagomir / Unkown
HY-RI02680A mmu-miR-145b antagomir / Unkown
HY-RI04235 rno-miR-145-3p inhibitor / Unkown
HY-RI04235A rno-miR-145-3p antagomir / Unkown
HY-B0185S Lidocaine-d10 N-Oxide / Unkown
HY-B0185S2 Lidocaine-d6 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mir145 NCBI NCBI:406937