TOP1 - DNA topoisomerase I Gene

Felis catus

Gene ID: 101093174 | Gene type: protein coding

About TOP1

mRNA	Protein	Name
XM_023251253.2	XP_023107021.1	DNA topoisomerase 1

Topoisomer_IB_N_htopoI_like

TOPEUc

Protein Preferred Names

Protein Names

DNA topoisomerase 1

topoisomerase (DNA) I

Approval

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-16560	Camptothecin		99.77%	Unkown

Clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Phase
HY-164734	Raludotatug Deruxtecan		99.29%	Phase 3
HY-171689	Puxitatug samrotecan	Inhibitor	98.51%	Phase 2
HY-168739	Topoisomerase I inhibitor 17		/	Phase 2
HY-171124	Tilatamig samrotecan	Inhibitor	95.26%	Phase 1
HY-U00248	LMP744	Inhibitor	98.85%	Phase 1
HY-U00248A	LMP744 hydrochloride	Inhibitor	99.08%	Phase 1
HY-18350	Indimitecan	Inhibitor	98.30%	Phase 1

Pre-clinical Phase

Bioactive Molecules (29)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-148819A	NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT hydrochloride	Inhibitor	98.46%	Unkown
HY-148819	NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT	Inhibitor	98.71%	Unkown
HY-163099	P5(PEG24)-VC-PAB-Exatecan		99.74%	Unkown
HY-153278	Q901	Inhibitor	98.38%	Unkown
HY-160005	LMP517	Inhibitor	99.58%	Unkown
HY-153278A	Q901 TFA	Inhibitor	/	Unkown
HY-N0114A	(±)-Evodiamine		99.74%	Unkown
HY-175203	Topi MF-6	Inhibitor	99.79%	Unkown
HY-W008874	meso-Tetra(4-pyridyl)porphine	Inhibitor	≥97.0%	Unkown
HY-RS14893	TOP1MT Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-118942	Topovale	Inhibitor	99.94%	Unkown
HY-126142	Top1 inhibitor 1	Inhibitor	99.67%	Unkown
HY-143265	Topoisomerase I inhibitor 2		/	Unkown
HY-144794	EGFR-IN-46		/	Unkown
HY-146437	Topoisomerase I inhibitor 6	Inhibitor	/	Unkown
HY-149348	DiPT-4		/	Unkown
HY-159935	Top1-IN-2	Inhibitor	/	Unkown
HY-161957	Top1/2-IN-1	Inhibitor	/	Unkown
HY-16560B	(R)-Camptothecin	Control	/	Unkown
HY-178036	ZM484	Inhibitor	/	Unkown
HY-180555	SN38-(PEG)2-Pom-α	Activator	/	Unkown
HY-181080	TOP1/TDP1-IN-1		/	Unkown
HY-18350A	Indimitecan hydrochloride	Inhibitor	/	Unkown
HY-N15249	4"-Isovalerylspiramycin I		/	Unkown
HY-RS14890	TOP1 Human Pre-designed siRNA Set A		/	Unkown
HY-RS14891	Top1 Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS14892	Top1 Rat Pre-designed siRNA Set A		/	Unkown
HY-W654323	PNU-142586 sodium	Inhibitor	/	Unkown
HY-133219	Guajadial C	Inhibitor	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P990947	Tilatamig	Inhibitor	99.99%	Unkown

Species	Symbol	Source	ID
Homo sapiens	TOP1	NCBI	NCBI:7150

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