5,8-Dimethoxyquinoxaline
5,8-Dimethoxyquinoxaline is a drug intermediate that can be used in studies related to organic synthesis. The derived cyclization product of 5,8-Dimethoxyquinoxaline specifically blocks TOP1-mediated DNA cleavage reactions.
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- CAS No.: 19506-19-5
- 화학식: C10H10N2O2
- 분자량:190.20
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
5,8-Dimethoxyquinoxaline serves as the core synthetic precursor of TU100 quinoxaline analogs; all its derivatives inhibit the viability of BT5 breast cancer and PC3 prostate cancer cells[1].
5,8-Dimethoxyquinoxaline undergoes oxidation and chlorination to yield a dichloro intermediate, which then undergoes cyclization to form indoloquinoxaline derivatives targeting TOP1[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 19506-19-5
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분자량 190.20
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화학식 C10H10N2O2
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SMILES
N=1C=CN=C2C1C(OC)=CC=C2OC
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)