NOX1 - NADPH oxidase 1 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 119868471

About NOX1

Primary_assembly X: 76,195,810-76,224,962 reverse strand.ROS_Cfam_1.0:CM025138.1

This gene has 3 transcripts (splice variants), 126 orthologues and 6 paralogues.

NOX1 Products (3)

mRNA Protein Name
XM_038450433.1 XP_038306361.1 NADPH oxidase 1 isoform X1
XM_038450435.1 XP_038306363.1 NADPH oxidase 1 isoform X3
XM_038450434.1 XP_038306362.1 NADPH oxidase 1 isoform X2

NOX1 Protein Structure

Ferric_reduct

Ferric_reduct: pfam01794 (65 - 214)

PLN02292

PLN02292: cl33451 (170 - 418)

NOX_Duox_like_FAD_NADP

NOX_Duox_like_FAD_NADP: cd06186 (296 - 563)

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  • 500
  • 564 a.a.
Protein Preferred Names Protein Names

NADPH oxidase 1

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0807A Prochlorperazine dimaleate Inhibitor ≥98.0% Unkown

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-12298 Setanaxib Inhibitor 99.81% Phase 2
HY-120801 APX-115 Inhibitor 99.90% Phase 2
HY-120801A APX-115 free base Inhibitor 99.54% Phase 2

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12805 ML171 Inhibitor 99.53% Unkown
HY-101499 GKT136901 Inhibitor 99.33% Unkown
HY-P1435 NoxA1ds Inhibitor 95.34% Unkown
HY-126195 Fluoflavine Inhibitor 98.47% Unkown
HY-105946 Hidrosmin Inhibitor 95.34% Unkown
HY-P1435A NoxA1ds TFA Inhibitor / Unkown
HY-174818 NOX5-IN-2 Inhibitor / Unkown
HY-174817 NOX5-IN-1 Inhibitor / Unkown
HY-148936 GLX481372 Inhibitor / Unkown
HY-183101 AMPAR modulator-12 Inhibitor / Unkown
HY-124487 GK-136901 Inhibitor / Unkown
HY-128004 ML171 analog 1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NOX1 NCBI NCBI:27035