CTLA4 - cytotoxic T-lymphocyte associated protein 4 Gene

Also Known as CD152; CTLA-4

Species: Bos taurus

Gene Type: protein coding
Gene ID: 281732

About CTLA4

Primary_assembly 2: 92,070,614-92,077,168 forward strand.ARS-UCD1.2:CM008169.2

This gene has 1 transcript (splice variant), 157 orthologues and 1 paralogue.

CTLA4 Products (1)

mRNA Protein Name
NM_174297.1 NP_776722.1 cytotoxic T-lymphocyte protein 4 precursor

CTLA4 Protein Structure

Ig

Ig: cl11960 (36 - 150)

Ig

Ig: cd00096 (51 - 55)

Ig

Ig: cd00096 (67 - 71)

Ig

Ig: cd00096 (109 - 113)

Ig

Ig: cd00096 (123 - 128)

Ig

Ig: cd00096 (140 - 144)

  • 0
  • 100
  • 200
  • 221 a.a.
Protein Preferred Names Protein Names

cytotoxic T-lymphocyte protein 4

  • cytotoxic T-lymphocyte antigen 4

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Inhibitory Antibodies (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-108829 Abatacept ≥99.0% Unkown
HY-P9901 Ipilimumab Inhibitor 99.88% Unkown
HY-P9918 Tremelimumab 99.50% Unkown

Clinical Phase

Inhibitory Antibodies (24)
Cat. No. Product Name Effect
Purity Phase
HY-P99540 Tuvonralimab Inhibitor 99.14% Phase 4
HY-P99117 Cadonilimab Inhibitor 99.87% Phase 3
HY-P990042 Gotistobart Inhibitor ≥99.0% Phase 3
HY-P990690 Volrustomig Inhibitor ≥99.0% Phase 3
HY-P99943 Erfonrilimab 99.98% Phase 3
HY-P99484 Botensilimab Inhibitor 99.00% Phase 3
HY-P99166 Vudalimab Inhibitor ≥99.0% Phase 2
HY-P99714 Lorigerlimab Inhibitor 97.5% Phase 2
HY-P99514 Zalifrelimab Inhibitor 98.28% Phase 2
HY-P990048 Muzastotug Inhibitor 99.48% Phase 2
HY-P99809 Quavonlimab Inhibitor ≥99.0% Phase 2
HY-P990080 Sovipostobart Inhibitor 96.528% Phase 2
HY-P990739 Evalstotug 95.062% Phase 2
HY-P990775 Vilastobart 99.63% Phase 2
HY-P991566 KD6001 Inhibitor / Phase 2
HY-P991960 JS007 / Phase 2
HY-P990703 Porustobart 99.70% Phase 1
HY-P99844 Davoceticept 99.9% Phase 1
HY-P990041 Firastotug Inhibitor 98.62% Phase 1
HY-P99709 Lodapolimab Inhibitor 99.71% Phase 1
HY-P99760 Nurulimab Inhibitor 95.00% Phase 1
HY-P991952 ADU-1604 Inhibitor / Phase 1
HY-P991953 BAT4706 / Phase 1
HY-P991961 REGN4659 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-159692 AZD8701 Inhibitor 96.61% Unkown
HY-120120 DZ-2384 Inhibitor / Unkown
HY-122081 CPI-644 Inhibitor / Unkown
HY-RS03299 CTLA4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03300 Ctla4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03301 Ctla4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-179228 AN02 / Unkown
Inhibitory Antibodies (17)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P99132 Anti-Mouse CTLA-4 Antibody (9D9) Inhibitor 98.91% Unkown
HY-108829A Abatacept (powder) Inhibitor 99.01% Unkown
HY-P990789 Anti-Mouse CTLA-4 Antibody (9H10) Inhibitor 99% Unkown
HY-P990256 Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) Inhibitor 98.68% Unkown
HY-P990945 Tazlestobart 99.66% Unkown
HY-P990722 Danvilostomig 98.38% Unkown
HY-P991139 Futermestotug Inhibitor 99.84% Unkown
HY-P99354 Bavunalimab 99.408% Unkown
HY-P990848 Anti-CTLA-4/CD152 Antibody (BN13) Inhibitor / Unkown
HY-P991951 ABA04 / Unkown
HY-P991959 JMW-3B3 Inhibitor / Unkown
HY-P992062 Anti-Mouse CD80 Antibody (TKMG48) Agonist / Unkown
HY-P992177 AI-025 Inhibitor / Unkown
HY-P992511 CS2009 Inhibitor / Unkown
HY-P991775 Anti-Rat CTLA-4 Antibody (WKH203) Inhibitor / Unkown
HY-P991827 Anti-Mouse CTLA-4 Antibody (UC10-4F10-11) Inhibitor / Unkown
HY-P991958 GIGA-564 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CTLA4 NCBI NCBI:1493