Davoceticept
Based on 1 Customer Validation
Davoceticept (ALPN-202; CD80 vIgD-Fc) is a variant CD80 vIgD-Fc fusion protein targeting CTLA-4 and PD-L1. Davoceticept consists of the (1-107) fragment of CD80 linked to IGHG1 Fc via a peptidyl linker. The expression system of Davoceticept is usually CHO (Chinese Hamster Ovary) cells.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 2307144-64-3
- Molecular Weight:77.425 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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[CD80 (B7-1, CD28LG1)fragment (1-107)]2-IGHG1 Fc (Fragment constant)
ELISA, FACS, Functional assay
Chemical Information
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CAS No. 2307144-64-3
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Appearance Liquid
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Molecular Weight 77.425 kDa
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Color Colorless to light yellow
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SMILES
[Davoceticept]
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Synonyms
ALPN-202; CD80 vIgD-Fc
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Shipping
Shipping with dry ice.
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (253 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Davoceticept. IMGT.
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)