TP53 - tumor protein p53 Gene

Also Known as P53

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 403869

About TP53

Primary_assembly 5: 32,665,394-32,678,755 reverse strand.ROS_Cfam_1.0:CM025104.1

This gene has 2 transcripts (splice variants), 256 orthologues and 3 paralogues.

TP53 Products (1)

mRNA Protein Name
NM_001389218.1 NP_001376147.1 cellular tumor antigen p53

TP53 Protein Structure

P53_TAD

P53_TAD: pfam08563 (5 - 29)

P53

P53: cd08367 (95 - 276)

P53_tetramer

P53_tetramer: pfam07710 (306 - 345)

  • 0
  • 100
  • 200
  • 300
  • 381 a.a.
Protein Preferred Names Protein Names

cellular tumor antigen p53

  • mutant P53 tumor suppressor protein

  • tumor protein p53 (Li-Fraumeni syndrome)

  • tumor suppressor p53

  • tumor suppressor protein

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-A0169A Methyl aminolevulinate hydrochloride Activator 98.98% Unkown
HY-A0169 Methyl aminolevulinate / Unkown
HY-A0169AR Methyl aminolevulinate hydrochloride (Standard) Activator / Unkown

Clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name Effect
Purity Phase
HY-15676 Idasanutlin 99.93% Phase 3
HY-19980 Eprenetapopt 99.52% Phase 3
HY-19980G Eprenetapopt (GMP) / Phase 3
HY-156633 Rezatapopt p53 Activator 99.78% Phase 2
HY-16271 Kevetrin hydrochloride 98.0% Phase 2
HY-171499 Cenersen Inhibitor 95.07% Phase 2
HY-16270 Kevetrin / Phase 2
HY-176083 ASTX295 99.81% Phase 1
HY-124036 DS-7423 Inhibitor 99.83% Phase 1

Pre-clinical Phase

Bioactive Molecules (48)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-10029 Nutlin-3a 99.13% Unkown
HY-P10925 Zolucatetide Inhibitor 99.31% Unkown
HY-P4210 Sulanemadlin Inhibitor 99.49% Unkown
HY-P1925A GO-203 TFA 98.39% Unkown
HY-15898 Y-320 99.03% Unkown
HY-19980A PRIMA-1 98.0% Unkown
HY-158039 YCH2823 99.87% Unkown
HY-148409 MMRi62 99.59% Unkown
HY-114231 Exaluren 98.0% Unkown
HY-D0892 NSP-DMAE-NHS 99.48% Unkown
HY-W181530 NCT02 98.14% Unkown
HY-17493 MI-773 96.29% Unkown
HY-107835 Flumethrin 99.29% Unkown
HY-179560 PMV6-PEG4-BI2536 Inhibitor 98.47% Unkown
HY-RS14912 TP53 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N1022 11-Hydroxytephrosin Inhibitor ≥98.0% Unkown
HY-RS14915 TP53BP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14922 TP53RK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-10029A (Rac)-Nutlin-3 98.18% Unkown
HY-100765 BI-0252 / Unkown
HY-107835R Flumethrin (Standard) / Unkown
HY-107835S Flumethrin-d5 / Unkown
HY-150620 BI-0282 Inhibitor / Unkown
HY-164828 Rezatapopt analog-1 / Unkown
HY-17493A MI-773 TFA 98.91% Unkown
HY-175000 L14-8 / Unkown
HY-178224 Morindone / Unkown
HY-180331 NVP-CFC218 Inhibitor / Unkown
HY-180371 NF-115 Inducer / Unkown
HY-183547 WEE1/PKMYT1-IN-4 Inhibitor / Unkown
HY-184116 A2AR/EGFR-IN-1 / Unkown
HY-184244 CAS-010 Inhibitor / Unkown
HY-186013 CML-07-119 Inducer / Unkown
HY-P11089 TP53 neoepitope Substrate / Unkown
HY-RS14913 Tp53 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14914 TP53AIP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14916 TP53BP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14917 TP53I11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14918 TP53I13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14919 TP53I3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14920 TP53INP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14921 TP53INP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15102 Trp53 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-164544 USP7-055 Inhibitor / Unkown
HY-174511 Human TP53 mRNA / Unkown
HY-183877 YO-2 / Unkown
HY-RS26028 Tp53i3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28596 Tp53inp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens TP53 NCBI NCBI:7157