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  3. Drug Derivative
  4. NF-115

NF-115 is a glycolipid inhibitor. NF-115 inhibits proliferation of glioma cancer cells and exhibits potent antimitotic activity in human astroblastoma cells. NF-115 can be used for research on glioma.

For research use only. We do not sell to patients.

NF-115

NF-115 Chemical Structure

CAS No. : 368870-53-5

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NF-115 Related Antibodies

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Description

NF-115 is a glycolipid inhibitor. NF-115 inhibits proliferation of glioma cancer cells and exhibits potent antimitotic activity in human astroblastoma cells. NF-115 can be used for research on glioma[1].

In Vitro

NF-115 exhibits potent antimitotic activitys in U-373 glioma cellswith an ID50 of 43 μM[1].
NF-115 (250-500 µM; 24 h) inhibits the proliferation of human U373-MG and T98G astrocytoma cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

NF-115 Related Antibodies
Molecular Weight

451.56

Formula

C21H41NO9
CAS No.
SMILES

O(CCCCCCCC)[C@@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](COCC(CO)(CO)CO)O1
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NF-115 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NF-115368870-53-5NF115NF 115Drug DerivativeDrug derivativehuman astroblastoma cellsGlcCerRac1-GDPlactosylceramideglycosphingolipid biosynthesisENU-induced primitive neuroectodermal tumourRhoA-GDPRho guanine nucleotide dissociation inhibitor 1galactosyltransferaseRhoGDI-1Inhibitorinhibitorinhibit

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