PARP3 - poly(ADP-ribose) polymerase family member 3 Gene
Species: Canis lupus familiaris (sub-species: familiaris)
Gene Type: protein coding
Gene ID: 484745
About PARP3
Primary_assembly 20: 38,117,895-38,124,368 reverse strand.ROS_Cfam_1.0:CM025119.1
This gene has 1 transcript (splice variant), 198 orthologues and 2 paralogues.
PARP3 Products (10)
| mRNA | Protein | Name |
|---|---|---|
| XM_038427600.1 | XP_038283528.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427602.1 | XP_038283530.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427598.1 | XP_038283526.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427601.1 | XP_038283529.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427599.1 | XP_038283527.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427602.1 | XP_038283530.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427600.1 | XP_038283528.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427601.1 | XP_038283529.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427599.1 | XP_038283527.1 | protein mono-ADP-ribosyltransferase PARP3 |
| XM_038427598.1 | XP_038283526.1 | protein mono-ADP-ribosyltransferase PARP3 |
PARP3 Protein Structure
WGR_PARP3_like
WGR_PARP3_like: cd08002 (57 - 155)
parp_like
parp_like: cd01437 (180 - 529)
- 0
- 100
- 200
- 300
- 400
- 500
- 531 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
poly [ADP-ribose] polymerase 3 LOW QUALITY PROTEIN: protein mono-ADP-ribosyltransferase PARP3 protein mono-ADP-ribosyltransferase PARP3 |
|
|
Related Agents
- Approval
- Clinical Phase
- Pre-clinical Phase
Approval
Bioactive Molecules
(11)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-10619 | Niraparib | Inhibitor | 99.96% | Yes |
| HY-10617A | Rucaparib | Inhibitor | 99.96% | Yes |
| HY-10619A | Niraparib hydrochloride | Inhibitor | 99.41% | Yes |
| HY-10617 | Rucaparib phosphate | Inhibitor | 99.76% | Yes |
| HY-10619B | Niraparib tosylate | Inhibitor | 99.99% | Yes |
| HY-102003 | Rucaparib monocamsylate | Inhibitor | 99.91% | Yes |
| HY-10619E | Niraparib tosylate hydrate | Inhibitor | 99.97% | Yes |
| HY-102003A | Rucaparib camsylate | Inhibitor | / | Unkown |
| HY-10617C | Rucaparib tartrate | Inhibitor | / | Unkown |
| HY-10617B | Rucaparib hydrochloride | Inhibitor | / | Unkown |
| HY-10617D | Rucaparib acetate | Inhibitor | / | Unkown |
Clinical Phase
Bioactive Molecules
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-13536 | AZD-2461 | Inhibitor | 99.79% | Phase 1 |
Pre-clinical Phase
Bioactive Molecules
(10)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-148566 | OUL232 | Inhibitor | 99.86% | Unkown |
| HY-150207 | RBN-3143 | Inhibitor | 99.29% | Unkown |
| HY-100225 | ME0328 | Inhibitor | 99.64% | Unkown |
| HY-148754 | PARP10-IN-3 | Inhibitor | 98.72% | Unkown |
| HY-155993 | YCH1899 | Inhibitor | 99.39% | Unkown |
| HY-148753 | PARP10-IN-2 | Inhibitor | 98.02% | Unkown |
| HY-W294889 | OUL245 | Inhibitor | / | Unkown |
| HY-100847 | AZ0108 | Inhibitor | / | Unkown |
| HY-178032 | PARP1-IN-44 | Inhibitor | / | Unkown |
| HY-172806 | PARP14 inhibitor 1 | Inhibitor | / | Unkown |
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