CCR5 - C-C motif chemokine receptor 5 Gene

Also Known as GPCR

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 484789

About CCR5

Primary_assembly 20: 42,775,514-42,780,191 reverse strand.ROS_Cfam_1.0:CM025119.1

This gene has 2 transcripts (splice variants), 151 orthologues and 22 paralogues.

CCR5 Products (1)

mRNA Protein Name
NM_001012342.3 NP_001012342.2 C-C chemokine receptor type 5

CCR5 Protein Structure

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (30 - 57)

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (30 - 307)

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (64 - 89)

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (100 - 130)

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (142 - 164)

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (190 - 219)

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (227 - 257)

7tmA_CCR5_CCR2

7tmA_CCR5_CCR2: cd15184 (275 - 300)

  • 0
  • 100
  • 200
  • 300
  • 352 a.a.
Protein Preferred Names Protein Names

C-C chemokine receptor type 5

  • C-C CKR-5

  • CC chemokine receptor 5

  • CC-CKR-5

  • CCR-5

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-13004 Maraviroc Antagonist 99.98% Yes
HY-117621A PF-04634817 succinate Antagonist 99.50% Unkown
HY-117621 PF-04634817 Antagonist 98.87% Unkown

Clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name Effect
Purity Phase
HY-14882 Cenicriviroc Antagonist 99.51% Phase 3
HY-14882A Cenicriviroc Mesylate Antagonist 99.94% Phase 3
HY-17377 Vicriviroc maleate Antagonist 99.91% Phase 3
HY-17450A Aplaviroc hydrochloride Antagonist 99.94% Phase 3
HY-17450 Aplaviroc Antagonist / Phase 3
HY-118962 E913 Antagonist / Phase 3
HY-P1034 DAPTA Inhibitor 99.40% Phase 2
HY-109593 BMS-813160 Antagonist 99.93% Phase 2
HY-101713 Ilacirnon Inhibitor 98.05% Phase 2
HY-14230 INCB9471 Antagonist / Phase 2
HY-19974 TAK-220 Antagonist 99.95% Phase 1

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13406 TAK-779 Antagonist 99.89% Unkown
HY-P4191A Met-RANTES (human) acetate Antagonist 99.39% Unkown
HY-111069 Nifeviroc Inhibitor 99.39% Unkown
HY-119101 AZD-5672 Antagonist 95.74% Unkown
HY-P4191 Met-RANTES (human) Antagonist / Unkown
HY-100261 CCR5 antagonist 1 Antagonist / Unkown
HY-107401 Ancriviroc Antagonist / Unkown
HY-152131 CCR5 antagonist 2 Antagonist / Unkown
HY-123902 Ophiobolin C Inhibitor / Unkown
HY-179607 LUF8100 Antagonist 98.64% Unkown
HY-111321 Fuscin Inhibitor / Unkown
HY-108432 BMS-741672 Antagonist / Unkown
HY-152132 CCR5 antagonist 3 Inhibitor / Unkown
HY-103406 PNU-177864 Inhibitor / Unkown
HY-162512 CB-0821 Inhibitor / Unkown
HY-119658 PF-4178903 Antagonist / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991653 HGS004 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CCR5 NCBI NCBI:1234
Mus musculus CCR5 NCBI NCBI:12774