CCR5 - C-C motif chemokine receptor 5 Gene

Canis lupus familiaris (sub-species: familiaris)

Also known as GPCR

Gene ID: 484789 | Gene type: protein coding

About CCR5

Primary_assembly 20: 42,775,514-42,780,191 reverse strand.ROS_Cfam_1.0:CM025119.1

This gene has 2 transcripts (splice variants), 151 orthologues and 22 paralogues.

mRNA	Protein	Name
NM_001012342.3	NP_001012342.2	C-C chemokine receptor type 5

7tmA_CCR5_CCR2

Protein Preferred Names

Protein Names

C-C chemokine receptor type 5

C-C CKR-5	CC chemokine receptor 5
CC-CKR-5	CCR-5

Approval

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13004	Maraviroc	Antagonist	99.98%	Yes
HY-117621A	PF-04634817 succinate	Antagonist	99.50%	Unkown
HY-117621	PF-04634817	Antagonist	98.87%	Unkown

Clinical Phase

Bioactive Molecules (11)

Cat. No.	Product Name	Effect	Purity	Phase
HY-14882	Cenicriviroc	Antagonist	99.51%	Phase 3
HY-14882A	Cenicriviroc Mesylate	Antagonist	99.94%	Phase 3
HY-17377	Vicriviroc maleate	Antagonist	99.91%	Phase 3
HY-17450A	Aplaviroc hydrochloride	Antagonist	99.94%	Phase 3
HY-17450	Aplaviroc	Antagonist	/	Phase 3
HY-118962	E913	Antagonist	/	Phase 3
HY-P1034	DAPTA	Inhibitor	98.87%	Phase 2
HY-109593	BMS-813160	Antagonist	99.93%	Phase 2
HY-101713	Ilacirnon	Inhibitor	98.05%	Phase 2
HY-14230	INCB9471	Antagonist	/	Phase 2
HY-19974	TAK-220	Antagonist	99.95%	Phase 1

Pre-clinical Phase

Bioactive Molecules (16)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-13406	TAK-779	Antagonist	99.89%	Unkown
HY-P4191A	Met-RANTES (human) acetate	Antagonist	99.39%	Unkown
HY-111069	Nifeviroc	Inhibitor	99.39%	Unkown
HY-119101	AZD-5672	Antagonist	95.74%	Unkown
HY-P4191	Met-RANTES (human)	Antagonist	/	Unkown
HY-100261	CCR5 antagonist 1	Antagonist	/	Unkown
HY-107401	Ancriviroc	Antagonist	/	Unkown
HY-152131	CCR5 antagonist 2	Antagonist	/	Unkown
HY-123902	Ophiobolin C	Inhibitor	/	Unkown
HY-179607	LUF8100	Antagonist	98.64%	Unkown
HY-111321	Fuscin	Inhibitor	/	Unkown
HY-108432	BMS-741672	Antagonist	/	Unkown
HY-152132	CCR5 antagonist 3	Inhibitor	/	Unkown
HY-103406	PNU-177864	Inhibitor	/	Unkown
HY-162512	CB-0821	Inhibitor	/	Unkown
HY-119658	PF-4178903	Antagonist	/	Unkown

Inhibitory Antibodies (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P991653	HGS004	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	CCR5	NCBI	NCBI:1234
Mus musculus	CCR5	NCBI	NCBI:12774

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