CB-0821
CB-0821 is a high affinity CCR5 inhibitor with a Ki of 0.04 nM. CB-0821 binds efficiently to the hydrophobic pocket of the CCR5 protein, to inhibit the interactions between viral protein and CCR5, thereby inhibiting viral entry. CB-0821 has the potential for anti-HIV research.
For research use only. We do not sell to patients.
- CAS No.: 81430-62-8
- Formula: C35H24N8
- Molecular Weight:556.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CCR5 0.04 nM (Ki) |
Chemical Information
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CAS No. 81430-62-8
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Molecular Weight 556.62
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Formula C35H24N8
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SMILES
C1(C2=NC3=NC(CC4=NN(C(C5=CC=CC=C5)=CC(C6=CC=CC=C6)=N7)C7=N4)=NN3C(C8=CC=CC=C8)=C2)=CC=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)