81430-62-8
81430-62-8
Chemical Structure
CB-0821
- CAS No.: 81430-62-8
- Formula:C35H24N8
- Molecular Weight:556.62
InChIKey: QFTLBEGGYAFYLK-UHFFFAOYSA-N
SMILES: C1(C2=NC3=NC(CC4=NN(C(C5=CC=CC=C5)=CC(C6=CC=CC=C6)=N7)C7=N4)=NN3C(C8=CC=CC=C8)=C2)=CC=CC=C1
Biological Activity: CB-0821 is a high affinity CCR5 inhibitor with a Ki of 0.04 nM. CB-0821 binds efficiently to the hydrophobic pocket of the CCR5 protein, to inhibit the interactions between viral protein and CCR5, thereby inhibiting viral entry. CB-0821 has the potential for anti-HIV research[1].
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CB-0821 | CB-0821 is a high affinity CCR5 inhibitor with a Ki of 0.04 nM. CB-0821 binds efficiently to the hydrophobic pocket of the CCR5 protein, to inhibit the interactions between viral protein and CCR5, thereby inhibiting viral entry. CB-0821 has the potential for anti-HIV research. | |||||||||||||||||||||
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References
Keywords
