MMP12 - matrix metallopeptidase 12 Gene

Species: Canis lupus familiaris (sub-species: familiaris)

Gene Type: protein coding
Gene ID: 611789

About MMP12

Primary_assembly 5: 28,969,618-28,984,462 forward strand.ROS_Cfam_1.0:CM025104.1

This gene has 2 transcripts (splice variants), 559 orthologues and 21 paralogues.

MMP12 Products (1)

mRNA Protein Name
NM_001287138.1 NP_001274067.1 macrophage metalloelastase precursor

MMP12 Protein Structure

PG_binding_1

PG_binding_1: pfam01471 (134 - 188)

Peptidase_M10

Peptidase_M10: pfam00413 (210 - 364)

HX

HX: cd00094 (382 - 555)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 571 a.a.
Protein Preferred Names Protein Names

macrophage metalloelastase

  • macrophage elastase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-101276 AZD-1236 Inhibitor 99.62% Phase 2

Pre-clinical Phase

Bioactive Molecules (22)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-156963 Aderamastat Inhibitor 99.82% Unkown
HY-120852 JG26 98.14% Unkown
HY-107639 UK-370106 Inhibitor ≥99.0% Unkown
HY-12093 MMP408 Inhibitor 99.04% Unkown
HY-135517 RXP470.1 Inhibitor 99.60% Unkown
HY-114091 PF-00356231 hydrochloride Inhibitor 99.52% Unkown
HY-164826 Acetyl zingerone 99.34% Unkown
HY-171804 Linvemastat Inhibitor 98.30% Unkown
HY-P4905 Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 Inhibitor 98.02% Unkown
HY-12093A (R)-MMP408 99.91% Unkown
HY-130391 MMP12-IN-3 Inhibitor ≥99.0% Unkown
HY-113621B Ageladine A dihydrochloride Inhibitor / Unkown
HY-114091A PF-00356231 Inhibitor / Unkown
HY-119185 AZD-6605 / Unkown
HY-120944 BAY-7598 Inhibitor / Unkown
HY-161707 MMP2-IN-4 Inhibitor / Unkown
HY-P6183 LXJ-02 Inducer / Unkown
HY-RS08522 MMP12 Human Pre-designed siRNA Set A / Unkown
HY-RS08523 Mmp12 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08524 Mmp12 Rat Pre-designed siRNA Set A / Unkown
HY-135517A (2R)-RXP470.1 Control 98.70% Unkown
HY-14155 MMP145 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MMP12 NCBI NCBI:4321