PAK4 - p21 (RAC1) activated kinase 4 Gene

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 696676

About PAK4

Primary_assembly 19: 38,371,839-38,424,824 forward strand.Mmul_10:CM014354.1

This gene has 3 transcripts (splice variants), 162 orthologues and 35 paralogues.

PAK4 Products (4)

mRNA Protein Name
XM_015123893.2 XP_014979379.2 serine/threonine-protein kinase PAK 4 isoform X1
XM_015123894.2 XP_014979380.2 serine/threonine-protein kinase PAK 4 isoform X1
XM_015123895.2 XP_014979381.2 serine/threonine-protein kinase PAK 4 isoform X2
XM_028839953.1 XP_028695786.1 serine/threonine-protein kinase PAK 4 isoform X1

PAK4 Protein Structure

CRIB_PAK_like

CRIB_PAK_like: cd01093 (9 - 47)

PKc_like

PKc_like: cl21453 (305 - 596)

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  • 597 a.a.
Protein Preferred Names Protein Names

serine/threonine-protein kinase PAK 4

  • p21(CDKN1A)-activated kinase 4

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-12793 Padnarsertib Inhibitor 99.58% Phase 2
HY-13007 PF-3758309 Inhibitor 99.79% Phase 1
HY-13007A PF-3758309 hydrochloride Inhibitor / Phase 1
HY-13007B PF-3758309 dihydrochloride Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19538 FRAX1036 Inhibitor 98.88% Unkown
HY-125035 LCH-7749944 Inhibitor 99.68% Unkown
HY-143490 PAK4-IN-2 Inhibitor 99.42% Unkown
HY-N8389 Globulol Inhibitor 99.74% Unkown
HY-159897 PAK4-IN-5 Inhibitor / Unkown
HY-146681 PAK1-IN-1 Inhibitor / Unkown
HY-111103A CZh226 hydrochloride Inhibitor / Unkown
HY-174247 CPS-021 Degrader / Unkown
HY-183941 SPU-106 Inhibitor / Unkown
HY-130628 PAK4-IN-1 Inhibitor / Unkown
HY-117218 KY-04045 Inhibitor / Unkown
HY-181092 PAK4-IN-7 Inhibitor / Unkown
HY-111103 CZh226 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PAK4 NCBI NCBI:10298