MMP12 - matrix metallopeptidase 12 Gene

Species: Macaca mulatta

Gene Type: protein coding
Gene ID: 703867

About MMP12

Primary_assembly 14: 96,136,915-96,151,182 reverse strand.Mmul_10:CM014349.1

This gene has 1 transcript (splice variant), 559 orthologues and 23 paralogues.

MMP12 Products (2)

mRNA Protein Name
XM_028833927.1 XP_028689760.1 macrophage metalloelastase isoform X2
XM_001098589.4 XP_001098589.2 macrophage metalloelastase isoform X1

MMP12 Protein Structure

PG_binding_1

PG_binding_1: pfam01471 (27 - 86)

Peptidase_M10

Peptidase_M10: pfam00413 (108 - 262)

HX

HX: cd00094 (278 - 469)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 470 a.a.
Protein Preferred Names Protein Names

macrophage metalloelastase

  • macrophage metalloelastase preproprotein

  • matrix metallopeptidase 12 (macrophage elastase)

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-156963 Aderamastat Inhibitor 99.88% Phase 3
HY-171804 Linvemastat Inhibitor 98.30% Phase 2
HY-101276 AZD-1236 Inhibitor 99.62% Phase 2

Pre-clinical Phase

Bioactive Molecules (20)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-120852 JG26 98.14% Unkown
HY-107639 UK-370106 Inhibitor ≥99.0% Unkown
HY-12093 MMP408 Inhibitor 99.04% Unkown
HY-135517 RXP470.1 Inhibitor 99.60% Unkown
HY-114091 PF-00356231 hydrochloride Inhibitor 99.52% Unkown
HY-164826 Acetyl zingerone 99.34% Unkown
HY-P4905 Mca-Pro-Leu-Gly-Leu-Glu-Glu-Ala-Dap(Dnp)-NH2 Inhibitor 98.02% Unkown
HY-12093A (R)-MMP408 99.91% Unkown
HY-130391 MMP12-IN-3 Inhibitor ≥99.0% Unkown
HY-113621B Ageladine A dihydrochloride Inhibitor / Unkown
HY-114091A PF-00356231 Inhibitor / Unkown
HY-119185 AZD-6605 / Unkown
HY-120944 BAY-7598 Inhibitor / Unkown
HY-161707 MMP2-IN-4 Inhibitor / Unkown
HY-P6183 LXJ-02 Inducer / Unkown
HY-RS08522 MMP12 Human Pre-designed siRNA Set A / Unkown
HY-RS08523 Mmp12 Mouse Pre-designed siRNA Set A / Unkown
HY-RS08524 Mmp12 Rat Pre-designed siRNA Set A / Unkown
HY-135517A (2R)-RXP470.1 Control 98.70% Unkown
HY-14155 MMP145 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MMP12 NCBI NCBI:4321