CTLA4 - cytotoxic T-lymphocyte associated protein 4 Gene

Macaca mulatta

Also known as CTLA-4

Gene ID: 705673 | Gene type: protein coding

About CTLA4

Primary_assembly 12: 91,268,710-91,274,863 forward strand.Mmul_10:CM014347.1

This gene has 1 transcript (splice variant), 157 orthologues and 1 paralogue.

mRNA	Protein	Name
NM_001044739.1	NP_001038204.1	cytotoxic T-lymphocyte protein 4 precursor

IgV_CTLA-4

Protein Preferred Names

Protein Names

cytotoxic T-lymphocyte protein 4

CD152 protein

Cat. No.	Product Name	Accession	Purity
HY-P72958	CTLA-4 Protein, Cynomolgus/Rhesus Macaque (HEK293, Fc)	Q9BDC4 (M1-D161)	≥95%
HY-P77345	CTLA-4 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)	Q9BDC4 (A37-D161)	≥95%

Approval

Inhibitory Antibodies (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P9901	Ipilimumab	Inhibitor	99.88%	Unkown
HY-108829	Abatacept		≥99.0%	Unkown
HY-P9918	Tremelimumab		99.50%	Unkown

Clinical Phase

Inhibitory Antibodies (10)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P99117	Cadonilimab		99.29%	Phase 3
HY-P99484	Botensilimab	Inhibitor	97.18%	Phase 3
HY-P990042	Gotistobart	Inhibitor	98.00%	Phase 3
HY-P99540	Tuvonralimab	Inhibitor	99.14%	Phase 3
HY-P99166	Vudalimab	Inhibitor	99.90%	Phase 2
HY-P99514	Zalifrelimab	Inhibitor	/	Phase 2
HY-P99809	Quavonlimab	Inhibitor	≥99.0%	Phase 2
HY-P99714	Lorigerlimab	Inhibitor	/	Phase 2
HY-P99844	Davoceticept		/	Phase 1
HY-P99760	Nurulimab	Inhibitor	95.00%	Phase 1

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Purity	Rare Diseases
HY-RS03299	CTLA4 Human Pre-designed siRNA Set A	/	Unkown
HY-RS03300	Ctla4 Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS03301	Ctla4 Rat Pre-designed siRNA Set A	/	Unkown

Inhibitory Antibodies (6)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-P99132	Anti-Mouse CTLA-4 Antibody (9D9)		≥98.0%	Unkown
HY-P990041	Firastotug	Inhibitor	/	Unkown
HY-P990048	Muzastotug	Inhibitor	/	Unkown
HY-P99354	Bavunalimab		/	Unkown
HY-P990080	Sovipostobart	Inhibitor	/	Unkown
HY-108829A	Abatacept (powder)	Inhibitor	/	Unkown

Species	Symbol	Source	ID
Homo sapiens	CTLA4	NCBI	NCBI:1493
Canis familiaris	CTLA4	NCBI	NCBI:403696
Macaca fascicularis	CTLA4	NCBI	NCBI:102115124
Mus musculus	CTLA4	NCBI	NCBI:12477
Rattus norvegicus	CTLA4	NCBI	NCBI:63835

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