2. Gene
  3. ZBED1 - zinc finger BED-type containing 1 Gene

ZBED1 - zinc finger BED-type containing 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
Homo sapiens

Also known as ALTE; DREF; TRAMP; hDREF

Gene ID: 9189 | Gene type: protein coding

About ZBED1

Cytogenetic location: Xp22.33 Genomic coordinates (GRCh38): X:2,486,435-2,500,976 (from NCBI)

This gene has 6 transcripts (splice variants), 117 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 10.8), colon (RPKM 10.6) and 25 other tissues.

Summary

This gene is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes. It was earlier identified as a gene with similarity to Ac transposable elements, however, was found not to have transposase activity. Later studies show that this gene product is localized in the nucleus and functions as a transcription factor. It binds to DNA elements found in the promoter regions of several genes related to cell proliferation, such as histone H1, hence may have a role in regulating genes related to cell proliferation. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene. [provided by RefSeq, Jan 2010]

ZBED1 Products(3)

mRNA Protein Name
NM_001171135.2 NP_001164606.1 E3 SUMO-protein ligase ZBED1
NM_001171136.2 NP_001164607.1 E3 SUMO-protein ligase ZBED1
NM_004729.4 NP_004720.1 E3 SUMO-protein ligase ZBED1

ZBED1 Protein Structure

zf-BED

zf-BED: BED zinc finger (23 - 72)

Dimer_Tnp_hAT

Dimer_Tnp_hAT: hAT family C-terminal dimerisation region (571 - 650)

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  • 600
  • 694 a.a.
Protein Preferred Names Protein Names

E3 SUMO-protein ligase ZBED1

Ac-like transposable element

Recombinant ZBED1 Proteins

Cat. No. Product Name Accession Purity
HY-P71047 ZBED1 Protein, Human (His) O96006 (N3-E100) ≥95%

Related Diseases

Diseases Alias
Fibrosclerosis Of Breast

Fibrosis Of The Breast

Breast Fibrosis
Sotos Syndrome 1

Sotos1

Sotos Syndrome, Type 1

Sotos' Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15954 ZBED1 Human Pre-designed siRNA Set A / Unkown