1. GPCR/G Protein
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  3. GLP-1 receptor agonist 7

GLP-1 receptor agonist 7 is a potent agonist of glucagon-like peptide-1 (GLP-1). GLP-1 receptor agonist 7 has the potential for the research of GLP-1-associated diseases, disorders, and conditions including diabetes mellitus (extracted from patent WO2021219019A1, compound 130b).

For research use only. We do not sell to patients.

GLP-1 receptor agonist 7 Chemical Structure

GLP-1 receptor agonist 7 Chemical Structure

CAS No. : 2736447-04-2

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5 mg USD 120 In-stock
10 mg USD 190 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

GLP-1 receptor agonist 7 is a potent agonist of glucagon-like peptide-1 (GLP-1). GLP-1 receptor agonist 7 has the potential for the research of GLP-1-associated diseases, disorders, and conditions including diabetes mellitus (extracted from patent WO2021219019A1, compound 130b)[1].

IC50 & Target

GLP-1[1]

Molecular Weight

593.05

Formula

C31H30ClFN4O5

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

OC(C1=CC=C2C(N(C(CN3CCC(C4=C(O[C@](C(C=CC(Cl)=C5)=C5F)([H])CO6)C6=CC=C4)CC3)=N2)C[C@@H]7CCO7)=N1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (210.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6862 mL 8.4310 mL 16.8620 mL
5 mM 0.3372 mL 1.6862 mL 3.3724 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6862 mL 8.4310 mL 16.8620 mL 42.1550 mL
5 mM 0.3372 mL 1.6862 mL 3.3724 mL 8.4310 mL
10 mM 0.1686 mL 0.8431 mL 1.6862 mL 4.2155 mL
15 mM 0.1124 mL 0.5621 mL 1.1241 mL 2.8103 mL
20 mM 0.0843 mL 0.4215 mL 0.8431 mL 2.1077 mL
25 mM 0.0674 mL 0.3372 mL 0.6745 mL 1.6862 mL
30 mM 0.0562 mL 0.2810 mL 0.5621 mL 1.4052 mL
40 mM 0.0422 mL 0.2108 mL 0.4215 mL 1.0539 mL
50 mM 0.0337 mL 0.1686 mL 0.3372 mL 0.8431 mL
60 mM 0.0281 mL 0.1405 mL 0.2810 mL 0.7026 mL
80 mM 0.0211 mL 0.1054 mL 0.2108 mL 0.5269 mL
100 mM 0.0169 mL 0.0843 mL 0.1686 mL 0.4215 mL
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GLP-1 receptor agonist 7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
GLP-1 receptor agonist 7
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HY-145412
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