1. GPCR/G Protein
  2. Glucagon Receptor
  3. Glucagon receptor antagonists-5

Glucagon receptor antagonists-5 

Cat. No.: HY-128781
Handling Instructions

Glucagon receptor antagonists-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonists-5 has potential for the treatment of type 2 diabetes mellitus (T2DM).

For research use only. We do not sell to patients.

Glucagon receptor antagonists-5 Chemical Structure

Glucagon receptor antagonists-5 Chemical Structure

CAS No. : 2200274-63-9

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Description

Glucagon receptor antagonists-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonists-5 has potential for the treatment of type 2 diabetes mellitus (T2DM)[1].

IC50 & Target

Ki: 32 nM (glucagon receptor)[1]

Molecular Weight

572.02

Formula

C₃₀H₂₉ClF₃N₃O₃

CAS No.

2200274-63-9

SMILES

O=C(NCCC(O)=O)C1=CC=C([[email protected]@H](N2N=CC3=C2C=C(C)C(C4=CC=C(C(F)(F)F)C=C4Cl)=C3)CC(C)C)C=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Glucagon receptor antagonists-5Glucagon receptor antagonists5Glucagon receptor antagonists 5Glucagon ReceptorGCGRInhibitorinhibitorinhibit

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Glucagon receptor antagonists-5
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HY-128781
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