2200274-63-9
Chemical Structure
Glucagon receptor antagonist-5
- CAS No.: 2200274-63-9
- Formula:C30H29ClF3N3O3
- Molecular Weight:572.02
IUPAC Name: (S)-3-(4-(1-(5-(2-chloro-4-(trifluoromethyl)phenyl)-6-methyl-1H-indazol-1-yl)-3-methylbutyl)benzamido)propanoic acid
InChIKey: DTVTXCDVEHSMQO-SANMLTNESA-N
SMILES: O=C(NCCC(O)=O)C1=CC=C([C@@H](N2N=CC3=C2C=C(C)C(C4=CC=C(C(F)(F)F)C=C4Cl)=C3)CC(C)C)C=C1
Biological Activity: Glucagon receptor antagonist-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonist-5 has potential for the treatment of type 2 diabetes mellitus (T2DM)[1].
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Glucagon receptor antagonist-5 | Glucagon receptor antagonist-5 (compound 13K) is a potent and orally bioavailable indazole-based glucagon receptor antagonist (Ki=32 nM). Glucagon receptor antagonist-5 has potential for the treatment of type 2 diabetes mellitus (T2DM). | |||||||||||||||||||||
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Keywords
