H2N-PEG2-CH2COOH hydrochloride
Based on 1 Customer Validation
H2N-PEG2-CH2COOH (hydrochloride) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 134979-01-4
- Formula: C6H14ClNO4
- Molecular Weight:199.63
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E649 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 134979-01-4
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Appearance Solid
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Molecular Weight 199.63
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Formula C6H14ClNO4
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Color White to off-white
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SMILES
O=C(COCCOCCN)O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (500.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.0093 mL | 25.0463 mL | 50.0927 mL | 125.2317 mL |
| 5 mM | 1.0019 mL | 5.0093 mL | 10.0185 mL | 25.0463 mL | |
| 10 mM | 0.5009 mL | 2.5046 mL | 5.0093 mL | 12.5232 mL | |
| 15 mM | 0.3340 mL | 1.6698 mL | 3.3395 mL | 8.3488 mL | |
| 20 mM | 0.2505 mL | 1.2523 mL | 2.5046 mL | 6.2616 mL | |
| 25 mM | 0.2004 mL | 1.0019 mL | 2.0037 mL | 5.0093 mL | |
| 30 mM | 0.1670 mL | 0.8349 mL | 1.6698 mL | 4.1744 mL | |
| 40 mM | 0.1252 mL | 0.6262 mL | 1.2523 mL | 3.1308 mL | |
| 50 mM | 0.1002 mL | 0.5009 mL | 1.0019 mL | 2.5046 mL | |
| 60 mM | 0.0835 mL | 0.4174 mL | 0.8349 mL | 2.0872 mL | |
| 80 mM | 0.0626 mL | 0.3131 mL | 0.6262 mL | 1.5654 mL | |
| 100 mM | 0.0501 mL | 0.2505 mL | 0.5009 mL | 1.2523 mL |
H2N-PEG2-CH2COOH hydrochloride Related Classifications
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