2. Apoptosis
  3. Apoptosis
  4. Hesperetin triacetate

Hesperetin triacetate is an active compound with anti-inflammatory and anti-tumor activities. Hesperetin triacetate inhibits bovine serum albumin denaturation in vitro. Hesperetin triacetate inhibits carrageenan-induced paw swelling in mice in vivo. Hesperetin triacetate exhibits anti-proliferative activity against breast cancer cells. Hesperetin triacetate induces DNA degradation and apoptosis in breast cancer cells. Hesperetin triacetate can be used in studies related to breast cancer and inflammation.

For research use only. We do not sell to patients.

Hesperetin triacetate

Hesperetin triacetate Chemical Structure

CAS No. : 73489-97-1

Size Stock
50 mg   Get quote  
100 mg   Get quote  
250 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Hesperetin triacetate Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Hesperetin triacetate is an active compound with anti-inflammatory and anti-tumor activities. Hesperetin triacetate inhibits bovine serum albumin denaturation in vitro. Hesperetin triacetate inhibits carrageenan-induced paw swelling in mice in vivo. Hesperetin triacetate exhibits anti-proliferative activity against breast cancer cells. Hesperetin triacetate induces DNA degradation and apoptosis in breast cancer cells. Hesperetin triacetate can be used in studies related to breast cancer and inflammation[1].

In Vitro

Hesperetin triacetate (compound 4b) potently inhibits the proliferation of human breast cancer MCF-7 cells at 48 h[1].
Hesperetin triacetate (36-48 h) induces apoptotic DNA fragmentation in human breast cancer MCF-7 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hesperetin triacetate Related Antibodies

Cell Proliferation Assay[1]

Cell Line: MCF-7 human breast cancer cells
Concentration: Concentrations to determine IC50
Incubation Time: 48 h
Result: Exhibited anti-proliferative activity against MCF-7 cells with an IC50 of 0.020 ± 0.001 μmol/mL.
In Vivo

Hesperetin triacetate (compound 4b) (5% cream formulation; topical administration; twice daily for 6 consecutive days) exhibits potent anti-inflammatory activity in a carrageenan-induced mouse paw edema model[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice treated carrageenan (22 ± 2 g)[1]
Dosage: 5% cream formulation
Administration: topical; twice daily; 6 days
Result: Reduced paw edema to 68.25 ± 5.68% at 3 hours post-carrageenan injection.
Reduced paw edema to 54.2 ± 10.5% at 1 day post-carrageenan injection.
Reduced paw edema to 46.34 ± 7.21% at 2 days post-carrageenan injection.
Reduced paw edema to 48.15 ± 5.36% at 3 days post-carrageenan injection.
Reduced paw edema to 36.41 ± 9.59% at 4 days post-carrageenan injection.
Reduced paw edema to 17.64 ± 6.35% at 5 days post-carrageenan injection.
Reduced paw edema to 19.67 ± 4.46% at 6 days post-carrageenan injection.
Molecular Weight

428.39

Formula

C22H20O9
CAS No.
SMILES

O(C(C)=O)C1=C2C(O[C@@H](CC2=O)C3=CC(OC(C)=O)=C(OC)C=C3)=CC(OC(C)=O)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Hesperetin triacetate Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hesperetin triacetate73489-97-1Apoptosisinflammationapoptosiscarrageenan-induced mouse paw edemabreast cancerMCF-7 human breast cancer cellsbreast cancer cellsDNA degradationapoptotic DNA fragmentationbovine serum albuminInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Hesperetin triacetate
Cat. No.:
HY-W778375
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.