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Cat. No.: HY-151197

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HIV protease-IN-1

HIV protease-IN-1 (compound 1·succinate) is a potent HIV protease non-peptidic inhibitor, can be used to research AIDS.

For research use only. We do not sell to patients.

CAS No.: 2511547-82-1
Formula: C₃₉H₄₀ClF₇N₁₀O₇
Molecular Weight:929.24

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

HIV protease-IN-1 Chemical Structure

CAS No.: 2511547-82-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

HIV protease-IN-1 (compound 1·succinate) is a potent HIV protease non-peptidic inhibitor, can be used to research AIDS^[1].

IC₅₀ & Target

HIV protease^[1]

Chemical Information

CAS No. 2511547-82-1
Molecular Weight 929.24
Formula C₃₉H₄₀ClF₇N₁₀O₇
SMILES

OC(CCC(O)=O)=O.FC(F)(F)C(C)(C)C[C@@]1(C2=CC=C(C3=NN(C4CC4)N=C3)C=C2)C(N(C(N)=N1)[C@@H](C5=CC(C6=NC=NN6C(F)F)=C(C=C5)Cl)COC(NC7(CC7)C(F)F)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Michael A. Ischay, et al. Process Development and Scale-Up of a Protease Inhibitor for the Treatment of HIV Featuring the Preparation of a Neopentyl Grignard Reagent and Development of a One-Pot Curtius Reaction. Org. Process Res. Dev. 2022.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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