hsa-miR-1307-5p antagomir
Based on 1 publication(s) in Google Scholar
hsa-miR-1307-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
For research use only. We do not sell to patients.
- Molecular Weight:7093.59
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications Citing Use of MedChemExpress (MCE) hsa-miR-1307-5p antagomir
More
Biological Activity
Description
Chemical Information
-
Molecular Weight 7093.59
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
-
miRBase Accession Number
-
Mature miRNA Sequence
UCGACCGGACCUCGACCGGCU
-
Stem-loop ID
hsa-mir-1307
-
Stem-loop Sequence
CAUCAAGACCCAGCUGAGUCACUGUCACUGCCUACCAAUCUCGACCGGACCUCGACCGGCUCGUCUGUGUUGCCAAUCGACUCGGCGUGGCGUCGGUCGUGGUAGAUAGGCGGUCAUGCAUACGAAUUUUCAGCUCUUGUUCUGGUGAC
-
Species
Human, Gorilla gorilla, Microcebus murinus, Nomascus leucogenys, Pteropus alecto
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Respir Res
MiR-1307-5p enhances fibroblast transdifferentiation to exacerbate chronic obstructive pulmonary disease through regulating FBXL16/HIF1α axis. [Abstract]2024 Oct 17;25(1):376. PMID: 39420370
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)