ICG-Sulfo-OSu sodium
Based on 1 Customer Validation
ICG-Sulfo-OSu sodium is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 90.26%
- CAS No.: 190714-28-4
- Formula: C49H52N3NaO10S2
- Molecular Weight:930.07
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
All PROTAC Linkers Isoforms
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Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 190714-28-4
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Appearance Solid
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Molecular Weight 930.07
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Formula C49H52N3NaO10S2
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Color Brown to black
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SMILES
O=S(C(C1)C(N(OC(CCCCCN2/C(C(C)(C)C3=C2C=CC4=CC=CC=C34)=C\C=C\C=C\C=C\C5=[N+](CCCCS(=O)([O-])=O)C6=C(C7=CC=CC=C7C=C6)C5(C)C)=O)C1=O)=O)(O[Na])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 62.5 mg/mL (67.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0752 mL | 5.3759 mL | 10.7519 mL | 26.8797 mL |
| 5 mM | 0.2150 mL | 1.0752 mL | 2.1504 mL | 5.3759 mL | |
| 10 mM | 0.1075 mL | 0.5376 mL | 1.0752 mL | 2.6880 mL | |
| 15 mM | 0.0717 mL | 0.3584 mL | 0.7168 mL | 1.7920 mL | |
| 20 mM | 0.0538 mL | 0.2688 mL | 0.5376 mL | 1.3440 mL | |
| 25 mM | 0.0430 mL | 0.2150 mL | 0.4301 mL | 1.0752 mL | |
| 30 mM | 0.0358 mL | 0.1792 mL | 0.3584 mL | 0.8960 mL | |
| 40 mM | 0.0269 mL | 0.1344 mL | 0.2688 mL | 0.6720 mL | |
| 50 mM | 0.0215 mL | 0.1075 mL | 0.2150 mL | 0.5376 mL | |
| 60 mM | 0.0179 mL | 0.0896 mL | 0.1792 mL | 0.4480 mL |