574 Results for "

ig-

" in MedChemExpress (MCE) Product Catalog:
Products (574)

574 Results for "ig-" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P99459
CAS No.: 909110-25-4
Synonyms: BG 9924; TT-47

Target:  

TNF Receptor CXCR

Research Areas:  

Inflammation/Immunology

Baminercept (BG 9924; TT-47) is an Ig fusion protein targeting the lymphotoxin β receptor (LTβR). Baminercept effectively regulates subsets of circulating immune cells by inhibiting LIGHT, LT-α1β2 and their receptors. Baminercept also increases blood lymphocyte counts and reduces plasma CXCL13 levels. Baminercept carries a high risk of hepatotoxicity. Baminercept can be used in research on rheumatoid arthritis and primary Sjögren's syndrome .
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2
2 Cited Publications
Cat. No.: HY-103358
CAS No.: 257292-29-8
Purity:  99.63%
Target:  

P-selectin

Research Areas:  

Inflammation/Immunology

KF38789 is a selective inhibitor of P-selectin-PSGL-1 binding. KF38789 inhibits the binding of U937 cells to immobilized P-selectin immunoglobulin G chimeric protein (P-selectin-Ig) with an IC50 value of 1.97 μM .
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2
2 Cited Publications
Cat. No.: HY-P73904
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig gamma chain C region
Species:  
Rabbit
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P74566
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3A; Sema III; Prev. SEMAD; Semaphorin D; Hsema-I; Semaphorin L; Coll-1; Collapsin 1; SEMA1; Hsema-III; SemD; SEMAIII; Sema Domain, Immunoglobulin Domain (ig), Short Basic Domain, Secreted, (Semaphorin) 3A; COLL1; Semaphorin III; SEMAL; Semaphorin-3A;
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-108801A
CAS No.: 862111-32-8
Purity:  97.66%

Target:  

VEGFR

Research Areas:  

Cardiovascular Disease Cancer

Aflibercept (VEGF Trap) is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease .
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1
1 Cited Publications
Cat. No.: HY-108801
CAS No.: 862111-32-8
Synonyms: VEGF Trap; VEGF-TRAPR1R2; VEGF-trapR1

Target:  

VEGFR

Aflibercept is a soluble decoy VEGFR constructed by fusing the Ig domains of VEGFR1 and VEGFR2 with the Fc region of human IgG1. Aflibercept inhibits VEGF signaling by reducing VEGF-regulated processes. Aflibercept can be used for thr research of age-related macular degeneration (AMD) and cardiovascular disease .
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1
1 Cited Publications
Cat. No.: HY-NP006
CAS No.: 308083-69-4
Synonyms: SPA
Protein A (SPA) is an immunoglobulin (Ig)-binding protein that exists on the bacterial surface and can be freely secreted into the extracellular environment. Protein A blocks opsonophagocytosis and induces B cell apoptosis in vitro by binding to the Fc region of antibodies and the Fab region of B cell receptors. Protein A can form toxic immune complexes with IgG, thereby inducing leukocyte necrosis. Protein A contributes to the virulence expression of Staphylococcus aureus. Protein A triggers allergic reactions in IgG-pretreated mouse models. Protein A can be used in studies related to immune system diseases .
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1
1 Cited Publications
Cat. No.: HY-P99446
CAS No.: 845264-92-8
Synonyms: TACI-ig; TACI-Fc 5

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Atacicept (TACI-Ig) is a is a recombinant fusion protein containing the extracellular, ligand-binding portion of the TACI receptor and the Fc portion of human IgG. Atacicept inhibits B cell stimulation by binding to B lymphocyte stimulator and a proliferation-inducing ligand. Atacicept can be used in research of B-cell autoimmune disease .
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1
1 Cited Publications
Cat. No.: HY-P99040
CAS No.: 1969313-51-6
Synonyms: JNJ-61610588; CI-8993; VSTB112

Target:  

VISTA

Research Areas:  

Cancer

Onvatilimab (JNJ-61610588) is a human IgG1κ anti-VISTA (V-domain Ig Suppressor of T-cell Activation) monoclonal antibody. Onvatilimab can be used in colorectal cancer research .
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1
1 Cited Publications
Cat. No.: HY-P73143
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: igHG1; ig Gamma-1 Chain C Region NIE; Immunoglobulin Heavy Constant Gamma 1 (G1m Marker); ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of igG1; ig Gamma-1 Chain C Region EU; Immunoglobulin Heavy Constant Gamma 1; ig Gamma-1 Chain C Region
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P77695
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: igHE; ig Epsilon Chain C Region; Immunoglobulin Heavy Constant Epsilon; Immunoglobulin Epsilon; Constant Region Of Heavy Chain Of igE; igE; ig Epsilon Chain C Region ND
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70796
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: igHG1; ig Gamma-1 Chain C Region NIE; Immunoglobulin Heavy Constant Gamma 1 (G1m Marker); ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of igG1; ig Gamma-1 Chain C Region EU; Immunoglobulin Heavy Constant Gamma 1; ig Gamma-1 Chain C Region
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P72603
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ig gamma-2A chain C region; Immunoglobulin heavy chain gamma polypeptide; ighg
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70771
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: igHG4; Immunoglobulin Heavy Constant Gamma 4; Immunoglobulin Heavy Constant Gamma 4 (G4m Marker); ig Gamma-4 Chain C Region; Immunoglobulin Heavy Chain Constant Region Gamma 4
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P79127
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SigLEC11; Siglec-11; Sialic Acid Binding ig Like Lectin 11; Sialic Acid Binding ig-Like Lectin 11; Sialic Acid-Binding ig-Like Lectin 11; Sialic Acid-Binding Lectin 11
Species:  
Human
Source:  
CHO
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1
1 Cited Publications
Cat. No.: HY-P70742
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SigLEC15; Sialic Acid-Binding ig-Like Lectin 15; Prev. CD33L3; SigLEC-15; CD33 Antigen-Like 3; Sialic Acid Binding ig-Like Lectin 15; HsT1361; Siglec-15; Sialic Acid Binding ig Like Lectin 15; CD33 Molecule-Like 3
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70845A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: MOG; MOG Alpha-5; Myelin Oligodendrocyte Glycoprotein; MOG AluA; Myelin-Oligodendrocyte Glycoprotein; MOG AluB; BTNL11; MOGig2; BTN6; NRCLP7; MOG ig-AluB
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P70052
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CXADR; CVB3-Binding Protein; CXADR Cell Adhesion Molecule; HCVADR; CAR; HCAR; Coxsackie Virus And Adenovirus Receptor; 46 KD Coxsackievirus And Adenovirus Receptor (CAR) Protein; Coxsackievirus And Adenovirus Receptor; CXADR, ig-Like Cell Adhesion Molecul
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P7639
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD276; Costimulatory Molecule; CD276 Molecule; B7 Homolog 3; CD276 Antigen; B7RP-2; B7-H3; 4ig-B7-H3; B7H3
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P71282A
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SEMA3C; Semaphorin-3C; Prev. SEMAE; Uncharacterized Protein SEMA3C; SemE; Semaphorin E; Sema Domain, Immunoglobulin Domain (ig), Short Basic Domain, Secreted, (Semaphorin) 3C; Semaphorin-E; Semaphorin 3C; Sema E
Species:  
Human
Source:  
HEK293
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