DOPE-PEG2000-MG1
DOPE-PEG2000-MG1 is an amphiphilic lipid-PEG-peptide conjugate comprising DOPE (1,2-dioleoyl-sn-glycero-3-phosphoethanolamine), PEG2000, and the MG1 peptide. MG1 peptide functions as a tumor-targeting ligand that specifically recognizes proteins overexpressed on tumor cell surfaces. DOPE-PEG2000-MG1 is used to modify liposomes and lipid nanoparticles for active tumor-targeted drug delivery.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
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Help & FAQs
生物活性
製品説明
体外実験
DOPE-PEG2000-MG1: surface decoration of liposomes and nanocarriers for tumor-targeted drug delivery, enabling selective accumulation in tumor tissues and enhanced cellular uptake by cancer cells.
Structural composition:
(1) DOPE; a phospholipid with two oleoyl chains that serves as a stable hydrophobic anchor in lipid bilayers and promotes pH-dependent membrane fusion for endosomal escape;
(2) PEG2000; a hydrophilic polymer chain that forms a protective hydration layer reducing immune recognition and extending blood circulation half-life;
(3) MG1 peptide; a targeting ligand that specifically binds to receptors or proteins overexpressed on tumor cell surfaces, acting as a navigation module to direct nanocarriers to tumor tissues for improved therapeutic efficacy and reduced systemic toxicity.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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SMILES
[DOPE-PEG2000-MG1]
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
DOPE-PEG2000-MG1 関連分類
HY-187495A 関連分類
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