NCAPH2 - non-SMC condensin II complex subunit H2 Gene

Also Known as CAPH2

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 29781

About NCAPH2

Cytogenetic location: 22q13.33 Genomic coordinates (GRCh38): 22:50,508,224-50,524,780 (from NCBI)

This gene has 10 transcripts (splice variants) and 191 orthologues. Ubiquitous expression in bone marrow (RPKM 17.2), testis (RPKM 13.4) and 25 other tissues.

Summary

This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010]

NCAPH2 Products (3)

mRNA Protein Name
NM_001185011.2 NP_001171940.1 condensin-2 complex subunit H2 isoform 3
NM_014551.5 NP_055366.3 condensin-2 complex subunit H2 isoform 1
NM_152299.4 NP_689512.2 condensin-2 complex subunit H2 isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
17268547 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NCAPH2 Protein Structure

CNDH2_N

CNDH2_N: Condensin II complex subunit CAP-H2 or CNDH2, N-terminal (51 - 605)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 605 a.a.
Protein Preferred Names Protein Names

condensin-2 complex subunit H2

  • CAP-H2 subunit of the condensin II complex

NCAPH2 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
NCAPH2 Q6IBW4 NCAPG2 Homo sapiens Q86XI2
Anti Tag CoIP
33961781
Intra
NCAPH2 Q6IBW4 NCAPG2 Homo sapiens Q86XI2
Pull Down
17268547
Intra
NCAPH2 Q6IBW4 NCAPG2 Homo sapiens Q86XI2
Anti Bait CoIP
17268547
Intra
NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Anti Tag CoIP
33961781
Intra
NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Anti Bait CoIP
17268547
Intra
NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Anti Tag CoIP
35271311
Intra
NCAPH2 Q6IBW4 SMC2 Homo sapiens O95347
Pull Down
17268547
Intra
NCAPH2 Q6IBW4 SMC4 Homo sapiens Q9NTJ3
Pull Down
17268547
Intra
NCAPH2 Q6IBW4 SMC4 Homo sapiens Q9NTJ3
Anti Tag CoIP
33961781
Intra
NCAPH2 Q6IBW4 NCAPD3 Homo sapiens P42695
Pull Down
17268547
Intra
NCAPH2 Q6IBW4 NCAPD3 Homo sapiens P42695
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

NCAPH2 抗体

製品番号 製品名 アプリケーション 反応性
HY-P83544 NCAPH2 Antibody (YA3289) WB, IHC-F, IHC-P, ICC/IF, IP Human
HY-P83544A NCAPH2 Antibody (YA3289)(PBS only) WB, IHC-F, IHC-P, ICC/IF, IP Human

関連疾患

Diseases Alias
Myopia 6

  • MYP6

  • Myopia, Susceptibility To

  • Myopia, Type 6
Fatal Infantile Cardioencephalomyopathy Due To Cytochrome C Oxidase Deficiency

  • Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency

  • Fatal Infantile Cox Deficiency

  • Fatal Infantile Cytochrome C Oxidase Deficiency

  • Fatal Infantile Encephalocardiomyopathy
Mitochondrial Complex Iv Deficiency, Nuclear Type 2

  • Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency 1

  • MC4DN2

  • Cemcox1

  • Mitochondrial Complex Ii Deficiency, Nuclear Type 4

  • MC2DN4

  • Mitochondrial Complex 2 Deficiency, Nuclear Type 4

  • Cytochrome C Oxidase Deficiency, Fatal Infantile, With Cardioencephalomyopathy

  • Fatal Infantile Cardioencephalomyopathy Due To Cytochrome C Oxidase Deficiency 1

  • Cytochrome C Oxidase Deficiency With Fatal Infantile Cardioencephalomyopathy

  • Cardioencephalomyopathy, Fatal Infantile, Due To Cytochrome C Oxidase Deficiency
Dilated Cardiomyopathy

  • Familial Dilated Cardiomyopathy

  • Primary Dilated Cardiomyopathy

  • Idiopathic Dilated Cardiomyopathy

  • Congestive Cardiomyopathy

  • Idiopathic Dilation Cardiomyopathy

  • Primary Familial Dilated Cardiomyopathy

  • Cardiomyopathy, Dilated

  • DCM

  • Cardiomyopathy, Familial Dilated

  • Dilated Cardiomyopathy, Familial

  • Hypokinetic Dilated Cardiomyopathy, Familial

  • Familial Idiopathic Cardiomyopathy

  • Fdc

  • Cardiomyopathy, Familial Idiopathic

  • Idiopathic Cardiomegaly

  • Dilated Congestive Cardiomyopathy

  • Chronic Dilated Cardiomyopathy

  • Ccm - [Congestive Cardiomyopathy]

  • Cocm - [Congestive Cardiomyopathy]

  • Dcm - [Dilated Cardiomyopathy]

  • Dilated-Hypokinetic Cardiomyopathy

  • Congestive Idiopathic Cardiomyopathy

  • Primary Idiopathic Dilated Cardiomyopathy
Pleural Empyema

  • Empyema

  • Pyothorax

  • Empyema, Pleural

  • Abscess Of Pleural Cavity

  • Abscess Of Thorax

  • Empyema Of Pleura

  • Empyema Of Pleura Without Fistula

  • Empyema With Fistula

  • Empyema With No Fistula

  • Empyema With Pleural Fistula

  • Empyema Without Mention Of Fistula

  • Empyema, Chest

  • Lung Empyema

  • Pleural Empyema With Fistula

  • Pleural Empyema With No Fistula

  • Purulent Pleurisy

  • Purulent Pleuritis

  • Thorax Abscess

  • Pyopneumothorax
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09071 NCAPH2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris NCAPH2 VGNC VGNC:43644
Rattus norvegicus NCAPH2 RGD RGD:1565937
Macaca mulatta NCAPH2 VGNC VGNC:75018
Felis catus NCAPH2 VGNC VGNC:63735
Bos taurus NCAPH2 VGNC VGNC:31906
Mus musculus NCAPH2 MGD MGI:1289164
Others NCAPH2 NCBI