NCAPH2 Antibody (YA3289)(PBS only)
(Synonyms: CAPH2)NCAPH2 Antibody (YA3289) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCAPH2.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-F, IHC-P, ICC/IF, IP
-
Reactivity :
Human
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
IHC-F
IHC-F: Immunohistochemistry-Frozen
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IP
IP: Immunoprecipitation
|
|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50-1:100 | 1:50-1:200 | 1:20 |
Product Details
NCAPH2 Antibody (YA3289) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCAPH2.
-
Host Rabbit
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 68 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 68 kDa
A synthetic peptide of human NCAPH2
Affinity Purified
Non-conjugated
IgG
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
NCAPH2 is a Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size. Seems to have lineage-specific role in T-cell development[1].
-
Subcellular Localization
Nucleus; Chromosome
-
Isoforms & Post-Translational Modification
Q6IBW4 has 4 isomers: Q6IBW4-1: 68227 Da (predicted); Q6IBW4-2: 65716 Da (predicted); Q6IBW4-5: 32819 Da (predicted); Q6IBW4-4: 68298 Da (predicted).
-
Subunit
Component of the condensin-2 complex, which contains the SMC2 and SMC4 heterodimer, and three non SMC subunits, NCAPG2, NCAPH2 and NCAPD3 that probably regulate the complex
-
SwissProt ID
-
Synonyms
CAPH2
-
Research Field
Cell Biology
Documentation
Powered by Bioz
