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PARP14 inhibitor 2

PARP14 inhibitor 2 (Compound 3) is an orally active and highly selective PARP14 inhibitor with an IC50 value of <30 nM. PARP14 inhibitor 2 inhibits the mono-ADP-ribosyltransferase activity of PARP14 and regulates IFN-γ and IL-4 signaling, reversing protumor macrophage polarization and inhibiting anti-tumor inflammatory responses. PARP14 inhibitor 2 is promising for research of PARP14-related diseases such as tumors, atopic dermatitis and autoimmune diseases.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • CAS 番号: 3064731-00-3
  • 分子式: C25H32FN3O4S
  • 分子量:489.60
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • PARP14 inhibitor 2 Chemical Structure
    PARP14 inhibitor 2 構造式
CAS 番号: 3064731-00-3
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    PARP14 inhibitor 2 Chemical Structure
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  • PARP14 inhibitor 2