CDC20-IN-1
CDC20-IN-1 (Compound E1) is a specific inhibitor of CDC20 and can be used in triple-negative breast cancer research. CDC20-IN-1 can induce autophagy in cancer cells and inhibit MDA-MB-231 cell proliferation, with an IC50 value of 1.43 μM.
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- 화학식: C19H22Cl3N7O4
- 분자량:518.78
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
6.47 μM
Compound: E1
|
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
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[PMID: 38364716] |
| L02 | IC50 |
14.66 μM
Compound: E1
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Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
Cytotoxicity against human L02 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
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[PMID: 38364716] |
| MCF7 | IC50 |
3.27 μM
Compound: E1
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Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
|
[PMID: 38364716] |
| MDA-MB-231 | IC50 |
1.43 μM
Compound: E1
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Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
|
[PMID: 38364716] |
| MDA-MB-468 | IC50 |
7.24 μM
Compound: E1
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Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 96 hrs by MTT assay
|
[PMID: 38364716] |
Chemical Information
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분자량 518.78
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화학식 C19H22Cl3N7O4
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SMILES
O=C(CC)NC(C(Cl)(Cl)Cl)N(C=N1)C2=C1C(NC3=CC(OC)=C(OC)C(OC)=C3)=NC(N)=N2
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CDC20-IN-1 Related Classifications
HY-161257 Related Classifications
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