Fshr - follicle stimulating hormone receptor Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 14309

Summary

Enables follicle-stimulating hormone receptor activity. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; gonad development; and regulation of signal transduction. Located in cell surface. Is expressed in early conceptus and gonad. Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis; ovarian dysgenesis 1; and ovarian hyperstimulation syndrome. Orthologous to human FSHR (follicle stimulating hormone receptor). [provided by Alliance of Genome Resources, Apr 2022]

Fshr Products (1)

mRNA Protein Name
NM_013523.3 NP_038551.3 follicle-stimulating hormone receptor precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables follicle-stimulating hormone receptor activity IDA
IDA: Inferred from direct assay
9206032 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Sertoli cell development IMP
IMP: Inferred from mutant phenotype
14998910 MGI
acts upstream of or within Sertoli cell proliferation IMP
IMP: Inferred from mutant phenotype
11466221 MGI
acts upstream of or within adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
16630814 MGI
acts upstream of or within adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
10330114 MGI
acts upstream of or within basement membrane organization IMP
IMP: Inferred from mutant phenotype
9811848 MGI
acts upstream of or within follicle-stimulating hormone signaling pathway IDA
IDA: Inferred from direct assay
10330114 MGI
acts upstream of or within intracellular water homeostasis IMP
IMP: Inferred from mutant phenotype
14998910 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
14502087 MGI
acts upstream of or within negative regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
11089565 MGI
acts upstream of or within neuron projection development IMP
IMP: Inferred from mutant phenotype
12204217 MGI
acts upstream of or within ovarian follicle development IMP
IMP: Inferred from mutant phenotype
9811848 MGI
acts upstream of or within ovulation cycle process IMP
IMP: Inferred from mutant phenotype
11089565 MGI
acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
10330114 MGI
acts upstream of or within positive regulation of intracellular estrogen receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
11089565 MGI
acts upstream of or within primary ovarian follicle growth IMP
IMP: Inferred from mutant phenotype
12801993 MGI
acts upstream of or within regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
12204217 MGI
acts upstream of or within regulation of acetylcholine metabolic process IGI
IGI: Inferred from genetic interaction
12204217 MGI
acts upstream of or within regulation of chromosome organization IMP
IMP: Inferred from mutant phenotype
14680821 MGI
acts upstream of or within regulation of hormone metabolic process IMP
IMP: Inferred from mutant phenotype
12204217 MGI
acts upstream of or within regulation of intracellular estrogen receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
18063689 MGI
acts upstream of or within regulation of osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
16630814 MGI
acts upstream of or within regulation of platelet-derived growth factor receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
16344272 MGI
acts upstream of or within regulation of protein phosphorylation IMP
IMP: Inferred from mutant phenotype
12204217 MGI
acts upstream of or within regulation of systemic arterial blood pressure IMP
IMP: Inferred from mutant phenotype
18599597 MGI
acts upstream of or within sperm DNA condensation IMP
IMP: Inferred from mutant phenotype
10775161 MGI
acts upstream of or within spermatid development IMP
IMP: Inferred from mutant phenotype
11466221 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
9811848 MGI
acts upstream of or within uterus development IMP
IMP: Inferred from mutant phenotype
10803590 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
16630814 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

follicle-stimulating hormone receptor

  • follitropin receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-P4190 Fsh receptor-binding inhibitor fragment(bi-10) Antagonist 99.19% Unkown
HY-12381 ML224 Antagonist 99.18% Unkown
HY-164764 ADX61623 Inhibitor 98.84% Unkown
HY-150210 FSHR agonist 1 Agonist 99.45% Unkown
HY-160857 TOP5668 Agonist 98.07% Unkown
HY-160856 TOP5300 Agonist / Unkown
HY-182705 Org 214444-0 / Unkown
HY-P10780 RFRP-3 (mouse) 98.82% Unkown
HY-RS05124 FSHR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W673613 ADX68692 Inhibitor / Unkown
HY-RS16988 Fshr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23431 Fshr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fshr NCBI NCBI:2492