TOP5300
(Synonyms: TOP05300)
TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats.
For research use only. We do not sell to patients.
- CAS No.: 1848981-48-5
- Formula: C28H29Cl2N5O4
- Molecular Weight:570.47
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Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
Description
TOP5300 is an orally active follicle-stimulating hormone receptor allosteric agonist. TOP5300 can induce the production of testosterone in stromal cells and promote follicular genesis and superovulation in rats[1].
In Vivo
Absorption, Distribution, Metabolism and Excretion (ADME) properties of TOP5300[1]
| Species | Dose (mg/kg) | AUCINF_obs (ng·h/mL) | t1/2 (h) | Cmax (ng/mL) | F (%) |
| Rat | 10 | 2655 | 5.1 | 237 | 20 |
| Mouse | 5 | 5533 | 2.5 | 1133 | 22 |
| Dog | 10 | 8719 | 391 | 32 |