TFPT - TCF3 fusion partner Gene

Also Known as FB1; amida; INO80F

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29844

About TFPT

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,107,020-54,115,657 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 109 orthologues and is associated with 46 phenotypes. Ubiquitous expression in brain (RPKM 11.2), prostate (RPKM 8.4) and 25 other tissues.

Summary

Predicted to enable DNA binding activity and protein kinase binding activity. Involved in apoptotic signaling pathway. Located in nucleoplasm. Part of Ino80 complex. [provided by Alliance of Genome Resources, Apr 2022]

TFPT Products (2)

mRNA Protein Name
NM_001321792.2 NP_001308721.1 TCF3 fusion partner isoform 2
NM_013342.4 NP_037474.1 TCF3 fusion partner isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17395368 GOA
Biological Process GO Annotation Evidence References Source
involved in apoptotic signaling pathway IDA
IDA: Inferred from direct assay
17041757 GOA
involved in chromatin remodeling IDA
IDA: Inferred from direct assay
21303910 GOA
involved in positive regulation of DNA-templated transcription IMP
IMP: Inferred from mutant phenotype
27641337 GOA
involved in regulation of DNA replication IMP
IMP: Inferred from mutant phenotype
25016522 GOA
involved in regulation of DNA strand elongation IMP
IMP: Inferred from mutant phenotype
25016522 GOA
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
26340092 GOA
involved in regulation of chromosome organization IMP
IMP: Inferred from mutant phenotype
26340092 GOA
Cellular Component GO Annotation Evidence References Source
part of Ino80 complex IDA
IDA: Inferred from direct assay
21303910 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

TCF3 fusion partner

  • INO80 complex subunit F

TFPT Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
TFPT P0C1Z6 UCHL5 Homo sapiens Q9Y5K5
Anti Tag CoIP
33961781
Intra
TFPT P0C1Z6 UCHL5 Homo sapiens Q9Y5K5
Anti Tag CoIP
18922472
Intra
TFPT P0C1Z6 CCDC57 Homo sapiens Q2TAC2-2
Validated Y2H
32296183
Intra
TFPT P0C1Z6 TFIP11 Homo sapiens Q9UBB9
BFG-2H
27107012
Intra
TFPT P0C1Z6 TFIP11 Homo sapiens Q9UBB9
Y2H Array
31515488
Intra
TFPT P0C1Z6 EAF2 Homo sapiens Q96CJ1
Y2H
17395368
Intra
TFPT P0C1Z6 EAF2 Homo sapiens Q96CJ1
Anti Tag CoIP
17395368
Intra
TFPT P0C1Z6 TPM3 Homo sapiens P06753
BFG-2H
27107012
Intra
TFPT P0C1Z6 TPM3 Homo sapiens P06753
Anti Tag CoIP
33961781
Intra
TFPT P0C1Z6 TPM3 Homo sapiens P06753
Validated Y2H
27107012
Intra
TFPT P0C1Z6 TRAF1 Homo sapiens Q13077
BFG-2H
27107012
Intra
TFPT P0C1Z6 TRAF1 Homo sapiens Q13077
Validated Y2H
27107012
Intra
TFPT P0C1Z6 PSMB1 Homo sapiens P20618
Validated Y2H
32296183
Intra
TFPT P0C1Z6 PIN1 Homo sapiens Q13526
Validated Y2H
32296183
Intra
TFPT P0C1Z6 C19orf25 Homo sapiens Q9UFG5
Validated Y2H
32296183
Intra
TFPT P0C1Z6 CCNDBP1 Homo sapiens O95273
BFG-2H
27107012
Intra
TFPT P0C1Z6 CCNDBP1 Homo sapiens O95273
Y2H
27107012
Intra
TFPT P0C1Z6 STK3 Homo sapiens Q13188
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Childhood Leukemia
B-Lymphoblastic Leukemia/Lymphoma With Hyperdiploidy

  • B-All With Hyperdiploidy

  • B Lymphoblastic Leukemia Lymphoma With Hyperdiploidy
Fundus Dystrophy

  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS14429 TFPT Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus TFPT VGNC VGNC:35795
Macaca mulatta TFPT VGNC VGNC:78378
Rattus norvegicus TFPT RGD RGD:620839
Canis familiaris TFPT VGNC VGNC:47303
Mus musculus TFPT MGD MGI:1916964
Felis catus TFPT VGNC VGNC:66125
Others TFPT NCBI